Surgical Oncology Flashcards
Goal of surgery
remove the malignant tumor
leave margin of adjacent normal tissue
minimal structural, functional, and cosmetic changes
Surgery depends on:
size
location
morbidity - effects on neighboring organs and structures
Onc Surgery uses:
prevention
diagnosis of primary site or metastatic disease
staging
cure with resection of disease (if local, DCIS)
reconstruction
vascular access (port, PIC, triple lumen cath)
control of disease (debulking)
onc emergencies (spinal cord compression)
paliation (reduce suffering, make comfortable)
Surgical diagnosis
tissue Required for new malig. diagnosis (except wilms in peds)
tissue for 1st recurrence for diagnosis
surgical biopsy required for tissue
Surgical diagnosis complications
inadequate tissue
FNA (fine needle aspiration)
Types of biopsies
Fine Needle Aspirate (FNA)
Core Needle Biopsy
FNA
small needle to aspirate cells from lesion
guided by palpation or imaging
used in head and heck cancers
preservation of future radiation field is needed
breast and lymph nodes
Core needle biopsy
larger needle to take cores of tissue
guided by palpation or imaging
yields adequate tissue for histology, little cosmetic problem
Clips may be inserted as landmarks
Treatment plans
may require chemo first if tumor mass is large
Sentinel lymph node biopsy (SLNB)
radioactive isotope 1st one from tumor is biopsied
“sentinel node” - first one next to
Node Mapping
radioactive dye injected into breast at tumor site
scan performed to visualize location of nodes
time of surgery - blue dye injected near tumor
scanner is used to find “hot nodes”
less invasive than tradiational dissection
Excisional Biopsy
completely removes suspicious lesion during surgical procedure (incision, laprosopic, thorascopic)
goal to remove lesion with a margin of normal around
Surgical Cytoreduction
- goal to reduce the overall tumor burden
- ultimate goal to remove all visible tumor and leave behind only nodules as small as 1-2mm
*debulking, removing some mass so chemo can work better
Cryosurgery
good results
brief period of subfreezing, cells dehydrate and metabolically deranged, resulting in apoptosis
does not ensure complete destruction, rarely used for cancer
Thermal surgery
minimizes operative blood loss
cells heated up to 140F, damages membrane and cell dies
Radiofrequency ablation
radiowaves
Laser surgery
aims beams of monochromatic light
focused energy on precise spot
Lung cancer
Wedge resection (part removed) Lobectomy Multiple lobectomies pneumonectomy minimally invasive