Surgical approach to CRC Flashcards

1
Q

2 methods used in CRC screening in the NHS

A
  • Faecal occult blood testing

* Flexible sigmoidoscopy – ‘Bowel scope’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does the NHS bowel cancer screening offer?

A

The NHS Bowel Cancer Screening Programme offers screening every two years to all men and women aged 60 to 75 (can opt in)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is used for the NHS screening?

A

FOBT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

When is a flexible sigmoidoscopy offered?

A

One off flexible sigmoidoscopy at 55 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

2 risks of flexi sigmoidoscopy?

A

Bleeding and perforation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

8 investigations used to establish a diagnosis of CRC

A
Blood tests
Tumour markers
Sigmoidoscopy (flexible)
Colonoscopy
CT colography
Barium enema
MR colography
BIOPSY
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

2 methods for staging CRC

A

Dukes’ – Dukes didn’t define Dukes’ stage D!

TNM- 1-4a (peritoneum)/b (other organ)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

5 staging investigations for CRC

A
CXR
Liver US
CT chest/abdo/pelvis
MRI rectum 
Endoanal US
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

5 methods of tumour spread

A
  • Direct- from structure to structure
  • Lymphatic
  • Blood-borne
  • Transcoelomic- spread within abdominal cavity
  • Implantation- cancer cells may be implanted into abdominal wound- unusual
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Define malignant polyp

A

An adenoma that appears benign macroscopically but in which there is invasion through the muscularis mucosae into the submucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is a pedunculated polyp?

A

They grow on a stalk up from the tissue.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is a sessile polyp?

A

A sessile polyp is one that is flat and does not have a stalk.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

3 aspects of follow up post-polyp/CRC surgery

A

• Endoscopy;
o Site check – 3 months & 9 months (BSG & ACP Guidelines)
o Polyp / Cancer dependent on number & size (BSG & ACP Guidelines)
• CEA
• CT TAP +/- MRI rectum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How do they mark up the area of the bowel that needs to be operated on?

A

Tattoo with Indian ink

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where can Indian ink not be used? (2)

A

Caecum and rectum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

4 aspects of preop care

A
  • Informed consent
  • Preparation for stoma
  • Group & Save or Cross match blood
  • Bowel preparation (+/- oral antibiotics)
17
Q

4 aspects of perioperative care

A
  • Thrombo-embolism prophylaxis (28 days)- standard is heparin (lmw) injections OD for 28 days
  • Antibiotic prophylaxis
  • Warming
  • Fluid balance
18
Q

Benefits of laparoscopic resection

A

shorter hospital stay
quicker return to normal activities
avoidance of incisional hernias
fewer intra-abdominal adhesions

19
Q

Complications of CRC surgery (11)

A
  • Visceral injury (spleen, ureter)
  • Anastomotic leakage
  • Wound infection
  • Urinary / sexual dysfunction
  • Defaecatory disturbances
  • Local recurrence
  • Death
  • Pneumonia
  • Myocardial infarction
  • DVT / PE
  • Distant recurrence
20
Q

Local and systemic factors affecting wound healing

A
•	Systemic factors
o	Age and Sex 
o	Nutrition 
o	Vitamin and trace element deficiencies - vitamin C, vitamin A, zinc 
o	Drugs – steroids, chemotherapy, immunosuppression 
o	Systemic disease – diabetes, jaundice, malignancy 
o	Hypoxia 
•	Local factors
o	Infection
o	Foreign bodies
o	Surgical techniques
o	Blood supply
o	Tension
21
Q

Which Duke’s stage has the best response to adjuvant chemotherapy

A

C

22
Q

What is the only cure for liver mets

A

Resection

23
Q

5 aspects of palliative care

A
  • Information
  • Symptom control
  • Psychological support
  • Social support
  • Spiritual support
24
Q

3 symptoms of emergency presentation of CRC

A
  • Obstruction - Overall up to 85% of colonic obstruction is due to malignancy
  • Peritonitis
  • Bleeding
25
Q

Diagnosis of emergency px CRC (3)

A

• Contrast studies

• CT Scanning
o Allows identification of site
o Stages the cancer

• Initial workup
o Plain radiology