Surgery SF Flashcards

1
Q

preferred primary tretment for GH-secreting microadenomas and macroadenomas

A

transphenoidal surgery

only prolactinoma has primary treatment of medical

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2
Q

signs of impending respiratory compromise in burns

A

hoarse voice
wheezing
stridor
subjective dyspnea (particularly concerning symptom)

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3
Q

type of necrotizing faciitis with a monobicrobial source

A

type 2
GABHS
MRSA

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4
Q

what to do for BIRADS 3

A

follow up after 6 months

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5
Q

% of malignancy for BIRADS 4B

A

11-50%

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6
Q

most robust indicators for burn mortality

A

AGE
BURN SIZE
INIHALATION INJURY
(REVISED BAUX SCORE)

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7
Q

neck zone with highest morbidity and mortality

A

zone I

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8
Q

amino acid most beneficial in the surgical critical patient

A

GLUTAMINE?
(primary nutrition source of small intestines)
-added in total parenteral nutrition

“With parenteral glutamine, the patients most likely to benefit are the critically ill and those at high risk of gut dysfunction. In such patients, a dose of 15–25 g per day may be sufficient.” (D’Souza & Powell-Tuck, 2004)

however

according to Schwartz (2019):
“Recently reported data from 2 large RCT in which critically ill patients received GLUTAMINE supplementation demonstrated INCREASED 6-MONTH MORTALITY in the patients who received glutamine. Therefore, glutamine supplementation in the critically ill patient is not currently recommended.”

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9
Q

best studied immune-nutrients

A

glutamine
arginine
omega-3 PUFA

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10
Q

Most abundant amino acid in the human body

A

GLUTAMINE (Schwartz)

-comprising nearly 2/3 of the free intracellular amino acid pool

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11
Q

preferred intubation for burn patients

A

orotracheal intubation

if with subjective dyspnea, elective ENDOTRACHEAL intubation?

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12
Q

2 large-bore IVs are ideal for burn largern than

A

40% TBSA

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13
Q

burn and prophylactic antibiotics

A

patients with acute burn injuries shouuld never receive prophylactic antibiotics

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14
Q

this acid causes liquefactive necrosis

A

hydrofluoric acid

  • causes hypocalcemia
  • topical application of calcium gluconate
  • IV calciu gluconate for systemic hypocalcemia symptoms
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15
Q

this acid has been known to cause hemolysis and hemoglobinuria

A

formic acid

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16
Q

BRCA1 is located on chromosome

A

17q

BRCA1
-tumor suppressor gene
-85% lifetime risk for BREAST CANCER
>>invasive ductal CA, poorly differentiated
>>hormone receptor negative (-/-/-)
-40% lifetime risk for OVARIAN CANCER
17
Q

BRCA2’s lifetime ovarian cancer risk

A

~20%

BRCA2
-chromosome 13q
-tumor suppressor gene
-bears NO homology to BRCA1
-85% breast cancer risk (same with BRCA1)
>>WELL-differentiated
>>express hormone receptors
18
Q

men with germline mutation sin BRCA__ have an estimated breast cancer risk of _____

A

BRCA 2
breast cancer risk of 6%
which represents a 100-fold increase over the risk in the general male population

19
Q

other assoc’d cancer for BRCA 2

A

OVARIAN
Colon
Prostate
Pancreatic

Gallbladder
Bile ducct
Stomach
MELANOMA