Surgery Antibiotics Flashcards

1
Q

Gram + Cocci

A

S.aureus
Streptococcus
Enterococcus

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2
Q

Gram + Bacilli (rods)

A

Clostridium (also anaerobic)
Lactobacillus (also anaerobic)
Corynebacterium
Streptomyces

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3
Q

Gram - Cocci

A

N.meningitidis
N.gonorrheae
M.catarrhalis

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4
Q

Gram - Bacilli (rods)

A
Enterobacteriaceae (E.coli, Kelbsiella, Enterobacter)
Pseudomonas
Haemophilus
Acinetobacter
Moraxella
Bacteroides
Campylobacter
Helicobacter
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5
Q

Pseudohyphae (non-bacterial species)

A

Candida

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6
Q

Drugs against MSSA (PO)

A

Dicloxacillin [gold standard]

Cephalexin (Keflex)

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7
Q

Drugs against MSSA (PO)

*PCN allergic alternatives

A

Doxycycline
TMP-SMX (Bactrim)
Clindamycin

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8
Q

Drugs against MSSA (IV)

A

Nafcillin [gold standard]
Cefazolin (Ancef)
Vancomycin

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9
Q

Drugs against MRSA (PO)

A
Bactrim (TMP-SMX)
Clindamycin
Doxycycline
Minocycline
Linezolid
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10
Q

Drugs against MRSA (IV)

A

Vancomycin [gold standard]
Linezolid
Tigecycline
Ceftaroline

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11
Q

Anti-Pseudomonal Drugs (PO)

A

Ciprofloxacin

Levofloxacin

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12
Q

Anti-Pseudomonal Drugs (IV)

A
Ciprofloxacin
Levofloxacin
Piperacillin/Tazobactam (Zosyn)
Ceftazidime or Cefepime
Tobramycin
Meropenem or Imipenem
Aztreonam
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13
Q

Anti-Anaerobic Drugs (PO)

A

Metronidazole (Flagyl) [gold standard]
Amoxicillin/Clavulanate (Augmentin) [gold standard]
Clindamycin

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14
Q

Anti-Anaerobic Drugs (IV)

A
PCN/B-lactamase inhibitor combo (Zosyn) [gold standard]
All carbepenems [gold standard]
Metronidazole (Flagyl) [gold standard]
Clindamycin
Cefoxitin
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15
Q

Anti-VRE Drugs (PO)

A

Linezolid or Tedizolid

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16
Q

Anti-VRE Drugs (IV)

A

Linezolid or Tedizolid
Daptomycin
Tigecycline
Telavancin

17
Q

Atypical PNA Infectious causes

A

Legionella
Chlamydia
Mycoplasma

18
Q

Atypical PNA Tx

A

Should cover both typical and atypical pathogens

PO tx options:

  1. Doxycycline
  2. Fluoroquinolone
  3. Macrolide
19
Q

SPACE Organisms

A
Serratia
Pseudomonas and Proteus
Acinetobacter
Citrobacter
Enterobacter
20
Q

SPACE Organisms Tx

A

Gram neg bacilli
Difficult to treat d/t resistance issues
Use empiric double coverage (from 2 drug classes) until culture sensitivities return

Tx Options:

  1. TMP-SMX
  2. Fluoroquinolones
  3. Carbapenems
  4. Aminoglycosides
21
Q

Multi-Drug Resistant Organisms: ESKAPE

A
Enterococcus (VRE)
Staphylococcus (MRSA)
Klebsiella (ESBL producing)
Acinetobacter
Pseudomonas
Enterobacter and E.Coli (ESBL producing)
22
Q

Fungal Organisms

A
Candidiasis (MC Candida albicans)
Cryptococcus
Histoplasmosis
Pneumocystis
Aspergillosis