Surgery Flashcards
Normal Bile Composition (3)
- Why ileal resection increase risk for stone?
- Why TPN patients increase risk for stone?
Bile = Cholesterol, Bile Salts, Phosphatidylcholine
- Ileal Resection = xBile Salt Reabsorption = supersaturated Chol bile = Chol Stones PPT
- TPN: lack of proteins/FFA in duodenum = xCCK stimulation = increase risk for stones
Chemo Tx Definitions
- Adjuvant/NeoAdjuvant
- Induction, Consolidation, Maintenance
- Salvage
Adjuvant = treatment given in addition to Sx NeoAdjuvant = treatment given just before surgery
Induction (initial dose killing to ≤5% tumor burden) –> Consolidation (further decrease burden) –> Maintenance (kill residual tumor to keep in remission)
Salvage: tx for disease after above standard regimens fail
MCC Syrinx (2)
- Congenital = 2/2 Arnold Chiari Malformation (herniation of cerbellar tonsils in FM; type I = +Syrinx, II = +Lumbar Myelocele)
- Spinal Trauma = CSF retention in central canal = Syrinx
Paralytic Ileus: 2 MCC
- vs. SBO
- vs. Ogivle’s?
Paralytic Ileus: complete distention of SI and LI (no bowel sounds)
- Intestinal Surgery (touching GI tract)
- Retroperitoneal Hemorrhage
vs. SBO: just distention of SI (think hyperactive bowel sounds)
vs. Ogilve’s: just large intestine
CAE Indications (2)
What to do for patients with stenosis who don’t meet criteria?
CAE in:
- Symptomatic patients 70-99% Stenosis
- Asymptomatic patients 60-99% Stenosis
If less, start ASA + Statin
4 Complications of PUD, Indicate MC*
Hemorrhage*
Perforation
Obstruction (Gastric Outlet)
Penetration
MC Thyroid Nodule
5 Thyroid Malignancies (MC –> LC)
Colloid
Papillary, Follicular, Medullary, Anaplastic, Lymphoma
MCCOD in Burn Patient
- with adequate resuscitation
- with inadequate resuscitation
- with adequate resuscitation = Septic Shock
- with inadequate resuscitation = Hypovolemic Shock
2x Reasons Ventilation hastens death in hypovolemic shock?
- PPV = increase thoracic pressure = decrease volume = decrease VR
- Anesthesia given dilates capacitance vessels = decrease VR
DPA+ (2)
DPL+ (2)
DPA+ = 10cc gross blood + feculent matter DPL+ = ≥100K RBC, ≥500 WBC
FAST shows fluid around spleen. Next step based on ___.
HDS
- If unstable –> EXLAP
- if stable –> CT
The reason is to try and avoid splenectomy at all costs for immune function, especially in kids.
Erectile Dysfunction s/p Trauma (2)
Neurogenic: a/w urethral injuries
Venogenic: a/w penile fracture (b/c tunica albuginea, where veins are, are damaged)
Early vs. Late Prosthetic Infection
- Timing
- Bug
- Tx
- Timing
Replacement
- Late = Replacement
Pt with breast cancer, wanting to start traztuzamab. Before doing so, need ____.
ECHO; cardiotoxic
Suspected Melanoma
- 1st step?
- Take margins @1st step?
- Margins for different thickness?
- When to get sentinel node study?
- 1st step? = Excisional Biopsy
- Take margins @1st step? NO!!! May interfere with lymph flow, difficult to ID sentinel node
- Margins for different thickness?
- 4mm = 3cm
- When to get sentinel node study? Depth >1mm
2 Fx of CO on O2-Dissociation Curve
5 Things that Shift Curve to Right
CO: Left Shift (b/c CO increase Hb affinity for CO AND for O2) and ∆Curve Shape
*Both decrease O2 delivery to tissue
Shift Curve Right = CBEAT
- CO2
- 2,3 BPG
- Exercise
- Acidosis/Altitude
- Temperature
**All things increase pO2 requirement to saturate Hb, making it easier to deliver O2 to tissues
Respiratory Quotient
- Define + Normal Value
- Value for Fats, Proteins, Carbs
- What if >1.0
- Define: ratio of CO2 production to O2 consumption, normally around 0.8.
- Represents average oxidation (O2 consumption) of fats (0.7), proteins (0.8) and carbs (1.0).
- If >1.0 = Mainly utilizing carbs
*guide nutrition in ICU patients
Acute Mediastinitis
- MCC (2)
- P/w
- CXR Finding
- Tx (3)
MCC = intraop infection of sternotomy wound + s/p esophageal rupture
P/w = purulent drainage from sternum
CXR finding = wide anterior mediastinum
Tx = Immediate Debridement + WOUND CLOSURE + Long term antibiotics
3 Signs of Tracheobronchial Performation + Management
- SubQ Emphysema
- Pneumomediastinum on CXR
- Persistent pneumothorax despite chest tube
Management = ABCs —> Bronch to locate injury —> repair
Uncomplicated vs. Complicated Diverticulitis Def + Management
When is colonic resection indicated? (4)
- Uncomplicated:
- LLQ Pain, Fever, CT with thickened colon +/- soft tissue stranding.
- Manage outpt with bowel rest, abx, pain rx - Complicated: IHOP (Infection, Hemorrhage, Obstruction, Perf)
- P/w above findings + IHOP (HOP managed as below)
- Abscess
Central Cord Syndrome
- Who gets it and how?
- Presentation?
- Think older patients with cervical DJD with hyperextension injury
- P/w damage to xCST»_space;> decussating spinothalamic tract
xMotor in arms, ok in legs (b/c morphology of fibers in CST with arms being more central)
Esophageal Varices
- Who needs screening?
- ASx Management
- Syx Management
- Screen ALL Cirrhotics
- ASx Management = Propranolol
- Sx Management = Octreotide / Endoscopic Scleropathy
Insulinoma (3) vs. Glucagonoma (4) Presentation. Tx of inoperable glucagonoma (2)?
Insulinoma = Whipple Triad
- Fasting HypoGluc
- Neurohypoglycemic Symptoms
- Resolve with Glucose
Glucagonoma = 4Ds
- Diabetes (mild)
- Dermatitis (NME)
- DVT
- Diarrhea
Tx
- Somatostatin
- Streptozocin
Early vs. Late Dumping Syndrome
- Timing
- Paph
- Management
Early
- Timing: Minutes after meal
- Paph: increase osmotic load to SI –> increase vasoactive peptides
- Tx: reassurance (will resolve), small meals, octreotide
Late
- Timing: hours later
- Paph: increase duodenal load = increase insulin release
- Tx: as above (except octreotide)