Surgery Flashcards
Example of depolarising neuromuscular drug
suxamethonium
key adverse events from suxamethonium
malignant hyperthermia
hyperkalaemia
reversal agent for malignant hyperthermia
IV dantrolene
MoA of suxamethonium
binds nACh, constant depolarisation of motor plate through non-competitive agonism
contraindications to suxamethonium
penetrating eye injuries
acute narrow angle glaucoma
this drug increases intra ocular pressure
use of suxamethonium
rapid sequence intubation
due to rapid onset and short duration of action
examples of non-depolarising neuromuscular blocking drugs
Tubocurarine, atracurium, vecuronium, pancuronium
MoA of non depolarising NMDs
Competitive antagonist of nicotinic acetylcholine receptors
main adverse effect of non depolarising NMD
hypotension
reversal agent for non depolarising NMD
neostigmine (Acetylcholinesterase inhibitor)
treatment of local anaesthetic toxicity
20% lipid emulsion
symptoms of local anaesthetic toxicity
agitation, confusion, dizziness, drowsiness, dysphoria, auditory changes, tinnitus, perioral numbness, metallic taste, and dysarthria
consequences of local anaesthetic toxicity
seizures, respiratory arrest, and/or coma.
drugs that can cause ED
beta blockers
SSRIs
most common type of prostate cancer
adenocarcinoma (95%)
most common type of bladder cancer
transitional cell carcinoma
which airway adjunct is suitable for a seizing patient
nasopharyngeal
RELATIVE contraindication for nasopharyngeal airway
basal skull fracture
what is the main complication of axillary lymph node clearance
lymphoedema and functional arm impairment
how is the risk of DVT reduced in superficial thrombophlebitis
LMWH
where is the lesion in subclavian steal syndrome
proximal stenotic lesion of the subclavian artery results in retrograde flow through vertebral or internal thoracic arteries
main presentation of subclavian steal syndrome
syncope
aetiology of aortic coarctation
aortic stenosis at site of ductus arteriosus
how does inflammatory breast cancer present
progressive erythema and oedema in the absence of signs of infection such as WCC or CRP, fever or discharge
what size lump is the cut off for wide local excision
< 4cm
what size lump is the cut off for mastectomy
> 4cm
first line treatment of lactational mastitis
12-24 hours of effective milk removal i.e. continue breastfeeding
don’t start Abx just because they present after one day of symptoms
features of duct ectasia
nipple retraction
milky or cheesy or green discharge
describe the breast screening programme in the NHS
for women between 50 to 70, screened every 3 years
Over 70s are usually not invited but can request screening via their GP
what is the chemotherapy treatment for node positive breast cancer
FEC-D chemotherapy
what is the chemotherapy treatment for node negative breast cancer requiring chemo
FEC chemotherapy
first line mx of patient with mild symptoms related to varicose veins [4]
elevate legs
compression stockings
lose weight
regular exercise
key investigation of varicose veins
venous duplex ultrasound
demonstrates retrograde flow
when should varicose veins be referred to vascular [5]
significant/troublesome lower limb symptoms e.g. pain, discomfort or swelling
previous bleeding from varicose veins
skin changes secondary to chronic venous insufficiency (e.g. pigmentation and eczema)
superficial thrombophlebitis
an active or healed venous leg ulcer
what are the surgical treatments for varicose
endothermal ablation: using either radiofrequency ablation or endovenous laser treatment
foam sclerotherapy: irritant foam → inflammatory response → closure of the vein
surgery: either ligation or stripping
4 skin changes associated with varicose veins/chronic venous insufficiency
varicose eczema (also known as venous stasis)
haemosiderin deposition → hyperpigmentation
lipodermatosclerosis → hard/tight skin
atrophie blanche → hypopigmentation
what poses the greatest risk to developing TRALI
infusion with plasma components
what is normal CVP
In a healthy adult, the normal range for CVP is typically between 2 to 8 mmHg (millimeters of mercury) when measured at the end of expiration while the individual is at rest and in a supine (lying down) position.
signs of bowel perforation
what investigation must be done
severe abdominal pain, guarding, and rigidity.
An erect chest X-ray is the most appropriate initial imaging study for suspected bowel perforation because it can detect free air under the diaphragm (pneumoperitoneum)
what are the indications for thoracotomy in haemothorax
> 1.5L blood drained initially or losses of >200ml per hour for >2 hours
which congenital hernias can be managed conservatively and which ones need repair ASAP
conservative for umbilical till 4-5years old
repair for inguinal
examples of benign liver lesions [8]
hemangiomas
Liver cell adenoma
Mesenchymal hamartomas
Liver abscess
Amoebic abscess
Hyatid cysts
Polycystic liver disease
Cystadenoma
which nerve is at risk of damage when doing a carotid endarterectomy
how does damage present?
hypoglossal
It presents as ipsilateral tongue deviation towards lesion.
preferred method of detecting free air in the abdomen
CT abdo
difference between incarcerated and strangulated hernias
strangulated ones are painful unlike incarcerated hernias
what is the general treatment of inguinal hernias
treat medically fit patients even if they are asymptomatic
i.e. refer routinely to open mesh repair
how are surgically unfit patients treated for inguinal hernias
a hernia truss
how are unilateral inguinal hernias treated compared to bilateral hernias
surgical approach
unilateral inguinal hernias are generally repaired with an open approach
bilateral and recurrent inguinal hernias are generally repaired laparoscopically
Parkland formula for burns fluid resus
how is resus fluid distributed over the 24 hours
SA% x body weight x 4ml gives fluid replacement over 24 hours
50% over the first 8 hours
50% over the next 16 hours
which fluids are used in burns resus
crystalloids only
Hartmans and Ringers
what fluids are used in burns resus after 24 hours
colloids including albumin and FFP
which analgesia should be avoided post kidney transplant
NSAIDs
What should you do to ascertain the anatomy and subtype of inguinal swelling?
press on the deep inguinal ring and ask the patient to cough
where in the body should lidocaine never be used
it must never be used near extremities due to the risk of ischaemia
radiological sign indicating free air in the abdomen
rigler’s sign
nerve lesion due to Posterior triangle lymph node biopsy
accessory nerve lesion
nerve lesion due to Lloyd Davies stirrups
common peroneal nerve