Surgery Flashcards
Hydromorphone
Brand Name(s): Dilaudid
Class: See pharm slides ; 1 mg Dilaudid = 6 mg morphine
MoA: Narcotic agonist-analgesic of opiate receptors; inhibits ascending pain pathways, which causes alteration in response to pain; produces analgesia, respiratory depression, and sedation; causes couph suppression by acting centrally in the medulla
Piperacillin/tazobactam
Brand Name(s): Zosyn
Class: Extended-spectrum PCN
MoA: Antipseudomonal penicillin plus beta-lactamase inhibitor; inhibits biosynthesis of cell wall mucopeptide synthesis by binding to 1 or more of the penicillin-binding proteins and is effective during active-multiplication stage.
Acetylcysteine
Brand Name(s): Mucomyst
Class: Pulmonary
MoA: Mucolytic activity through its sulfhydryl group, which opens up disulfide bonds in the mucoproteins and lowers mucous viscosity of pulmonary secretions
Indxn:
Contraindxn:
Leuprolide
Brand Name: Lupron
Class: Antineoplastic,
MoA: Agonist analogue of luteinizing hormone-releasing hormone (LHRH). When administered continuously, decreases LH and FSH levels by acting as potent inhibitor of gonadotropin secretion; decrease in LH and FSH levels followed by suppression of ovarian and testicular steroidogenesis; testosterone levels reduced to below castrated levels in males
Indxn:
Contraindxn:
Tamoxifen
Brand
Chlordiazepoxide
Brand Name: Librium
Propofol
Brand Name: Diprivan
Class: General anesthetics, System
MoA:
Rifaximin
Brand Name:
Fidaxomicin
Brand Name:
Imipenem
Brand Name:
Dexmedetomidine
Brand Name: Precedex
Class: Sedative
MoA: Centrally acting alpha2-adrenoceptor agonist that has sedative and anesthetic properties possibly by activating G-proteins in the brainstem, which results in the inhibition of norepinephrine release
** Doesn’t cause respiratory depression or hypotension
