Surg - Dr Oaks Flashcards
acute phase of post surg recovery
first 24 hr
peripheral vasoconstriction
hypothermia
blood shunts to vital organs
subsequent reparative phases
days 2-14
multitude mechanisms = healing
cortisol role in healing
promotes PRO breakdown and gluconeogenesis in liver = high blood glucose
promotes lipolysis and has anti-inflammatory properties
catecholamine role in healing
adrenal gland releases
glycogenolysis, pro breakdown and lipolysis
GH role in healing
promotes pro synthesis, stops pro breakdown, promote lipolysis and inhibits glucose uptake by cells
adh levels post surg are..
elevated
insulin secretion post surge is
blunted while glucagon secretion slightly elevates
net effect that leads to healing
- salt and water retention = keeps CV stable
2. increased catabolism = energy sources
what 3 main cytokines play major role in surg
IL 1 TNF alpha and IL6
fever, leukocytosis
how do cytokines affect liver?
increase acute phase proteins such as CRP, fibrinogen and alpha 2 macroglobulin
primary extracellular ion
sodium
primary intracellular ion
potassium
adults generally need ___ fluids per day
30 ml per kg
first 10 kg = 100ml/kg/d
10-20 kg = + 50 ml/kg/d
over 20 kg = + 20 ml/kg/day
t/f sepsis causes third spacing
true
for surgical pts they need ___ for nutrition per day
30 kcal/kg/day
for renal pts want nutrition with
less fuild and less protein