Surg - Dr Oaks Flashcards

1
Q

acute phase of post surg recovery

A

first 24 hr
peripheral vasoconstriction
hypothermia
blood shunts to vital organs

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2
Q

subsequent reparative phases

A

days 2-14

multitude mechanisms = healing

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3
Q

cortisol role in healing

A

promotes PRO breakdown and gluconeogenesis in liver = high blood glucose
promotes lipolysis and has anti-inflammatory properties

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4
Q

catecholamine role in healing

A

adrenal gland releases

glycogenolysis, pro breakdown and lipolysis

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5
Q

GH role in healing

A

promotes pro synthesis, stops pro breakdown, promote lipolysis and inhibits glucose uptake by cells

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6
Q

adh levels post surg are..

A

elevated

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7
Q

insulin secretion post surge is

A

blunted while glucagon secretion slightly elevates

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8
Q

net effect that leads to healing

A
  1. salt and water retention = keeps CV stable

2. increased catabolism = energy sources

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9
Q

what 3 main cytokines play major role in surg

A

IL 1 TNF alpha and IL6

fever, leukocytosis

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10
Q

how do cytokines affect liver?

A

increase acute phase proteins such as CRP, fibrinogen and alpha 2 macroglobulin

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11
Q

primary extracellular ion

A

sodium

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12
Q

primary intracellular ion

A

potassium

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13
Q

adults generally need ___ fluids per day

A

30 ml per kg

first 10 kg = 100ml/kg/d
10-20 kg = + 50 ml/kg/d
over 20 kg = + 20 ml/kg/day

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14
Q

t/f sepsis causes third spacing

A

true

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15
Q

for surgical pts they need ___ for nutrition per day

A

30 kcal/kg/day

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16
Q

for renal pts want nutrition with

A

less fuild and less protein

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17
Q

for hepatic pt want __ in nutrition

A

less nitrogen

avoid encephalopathy

18
Q

for pulm pts want nutrition with

19
Q

t/f parenteral feeding is far superior to enteral feeding

A

FALSE

enteral is WAY better

20
Q

enteral feeding

A

is through GI tract

21
Q

parenteral feeding is via

22
Q

if see higher rates of nitrogen excreted post op..

A

sign they are in very catabolic stage need higher caloric post op!

23
Q

3 phases of wound healing

A

hemostasis with inflammation
proliferation
maturation

24
Q

what occurs during proliferation phase of wound healing

A

after first few days last several weeks and
type III collage laid down and replaced by type I
growth of new BV and epithelial cells

25
maturation starts when?
after 2-3 wks injury lasts couple mo | MMPS break down collagen, scar remodeling, myofibroblasts - secondary intention
26
what vitamins and minerals are needed for collagen synthesis?
zin, copper and MN, vit a and c
27
why obese pts at risk for wound infection?
fat is not well vascularized - slows down healing process and ability to fight off infection
28
why do DM struggle with wound healing?
hyperglycemia impairs neutrophil function and fibroblast function
29
CT diseases and wound healing..whats problem?
can be associated with vasculitis and slower healing and impaired blood flow also may be IC or on meds that make IC
30
smoking induces vasoconstriction and reduces skin blood flow up to about ___ for ___
reduces blood flow to 40% for 90 min! reduces possibility to heal quickly!
31
smokers have what 6 factors that impair healing
``` decreased tissue oxygen low levels of vit c (needed for collagen synthesis) low levels of collagen synthesis impaired neutrophil phagocytic activity endothelial cell dysfunction enhanced thrombus formation ```
32
a fever over ___ is common and is ___
over 38 degrees celcius | not always indicator of a wound infection
33
6 W of fever post op
``` wind - atelectasis water - UTI/ anastomotic leak wound - site infxn walking - DVT/ PE Wonder - drugs ``` days: 1, 3, 5, 7, over 9 .. then ask why else did we do?
34
clip don't ____ for prvt site infections
clip don't shave off hair
35
abx before surgery?
yes to prvt infxn but stop within 48 hours to avoid resistance
36
examples of bacteria that can cause necrotizing fascitis
GAS, S. aureus, clostridium perfringens, bacteroides fragilis and aeromonas hydrophila, often combo of bacteria!!
37
what suture type has higher infection risk?
multifilament - more surface area
38
soft tissue expansion is most often used in..
breast reconstruction surgery
39
ftsg vs stsg
full thickness: includes entire epidermis and dermis leaving behind a wound, appear more normal, undergo minimal contraction
40
split thickness graft
whole epidermis but part of dermis behind often not that appealing contracts with time more fragile but lower failure rate because thinner covers larger surface area because of meshing option
41
NPWT is what?
wound vac or negative pressure wound therapy