Supportive ‘Cytoprotective’ Drugs Flashcards
1
Q
Allopurinol
A
Prevent buildup of uric acid
2
Q
Rasburicase
A
Decrease risk for tumor lysis syndrome (TLS)
3
Q
Amifostine
A
Prevent xerostomia from high-dose radiation therapy and protect the kidney and bone marrow from certain chemotherapeutic drugs
4
Q
Dexrazoxane
A
Prevent heart damage from anthracyclines
5
Q
Leucovorin (folinic acid)
A
Reduce the severity of side effects when high doses of Methotrexate are used. (not administered on the same day)
6
Q
Mesna
A
Prevent bladder toxicity associated with Cyclophosphamide and Ifosfamide
7
Q
Colony-stimulating Factors (CSFs) e.g. Filgrastim
A
Raise blood cell counts.
Filgrastim — specifically stimulates the proliferation and differentiation of granulocyte precursors, leading to an increase in neutrophils (hence its use in neutropenia).
