Sun Flashcards

0
Q

NCC to maxillary and mandibular

A

Dlx

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1
Q

NCC to bronchial arches

A

Hox

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2
Q

Ectodermal epithelium signaling pathways

A

BMP
FGF
Wnt
SHH

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3
Q

Mesenchyme transcription factors

A
Msx
Dlx
Pax
Gli
Runx
Barx
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4
Q

Steps in crown development

A
  1. Initiation
  2. Morphogenesis
  3. Differentiation & mineralization
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5
Q

Root dentin formation chemicals involved

A

Lamini-5
TGF-Beta
Nfic

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6
Q

Primary initial mineralization

A

15-19 wks IU

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7
Q

Primary completed mineralization

A

2-11 months PN

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8
Q

Permanent initial mineralization

A

Birth-9 yrs

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9
Q

Permanent completed mineralization

A

5-14 yrs

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10
Q

Fate of HERS

A
Become epithelial rest of Malassez
Apoptosis
Incorporate into cementum front
Epithelial mesenchymal transformation
Mitigation to PDL
Differentiate to cementoblasts
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11
Q

Gene mutations known to be related to missing teeth

A
Msx1
Pax9
Axin2
EDA
p63
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12
Q

Gene mutations for supernumerary teeth

A

Runx2

Apc

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13
Q

Msx1

A

Transcription factor

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14
Q

Pax9

A

Transcription factor

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15
Q

Axin2

A

Signaling molecule

Wnt pathway

16
Q

EDA

A

Signaling molecule

TNF pathway

17
Q

p63

A

Transcription factor

Critical for BMP, FGF, SHH

18
Q

Runx2

A

Transcription factor

19
Q

Apc

A

Signaling molecule

Wnt pathway