Summary Antibiotics 2

Question 1

Antibiotics

Answer 1

inhibit bacterial growth in the host by interfering with critical
cellular processes in the bacteria and exploiting the differences
between bacterial physiology and host physiology to achieve selectivity

Question 2

which types of antibiotics target cell wall biosynthesis at distinct steps

Answer 2

•B-lactams, glycopeptides, bacitracin, cycloserine, daptomycin and
polymyxin

Question 3

Which antibiotics target early stages of

protein synthesis

Answer 3

•tetracyclines, aminoglycosides, and linezolid

Question 4

Which antibiotics target elongation stage of protein synthesis

Answer 4

macrolides, chloramphenicol, and clindamycin

Question 5

Which antibiotics inhibit DNA gyrase to produce DNA damage

Answer 5

fluoroquinolones

Question 6

Which antibiotic targets DNA metabolism in anaerobic bacteria

Answer 6

metronidazole

Question 7

Which antibiotics are antimetabolites that are competitive inhibitors of normal metabolic reactions

Answer 7

trimethoprim, sulfonamides

Question 8

Resistance

Answer 8

has emerged to nearly all antibiotics in clinical use, often
facilitated by genetic transfer of resistance determinants between
bacteria