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Shared Enzymes > Substrates, Inducers, Inhibitors > Flashcards

Substrates, Inducers, Inhibitors Flashcards

1
Q

amitriptyline

A

CYP2C19 substrate
CYP2D6 substrate & inhibitor
CYP3A4 substrate

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2
Q

citalopram

A

CYP2C19 substrate

CYP3A4 substrate

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3
Q

diazepam

A

CYP2C19 substrate

CYP3A4 substrate

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4
Q

esomeprazole

A

CYP2C19 substrate & inhibitor

CYP3A4 substrate

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5
Q

omeprazole

A

CYP2C19 substrate & inhibitor

CYP3A4 substrate

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6
Q

phenytoin

A

CYP2C19 substrate & inducer

CYP3A4 inducer

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7
Q

voriconazole

A

CYP2C19 substrate & inhibitor

CYP3A4 substrate & inhibitor

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8
Q

(R)-warfarin

A

CYP2C19 substrate

CYP3A4 substrate

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9
Q

cimetidine

A

CYP2C19 inhibitor
CYP2D6 inhibitor
CYP3A4 inhibitor

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10
Q

fluconazole

A

CYP2C19 inhibitor

CYP3A4 inhibitor

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11
Q

fluoxetine

A

CYP2C19 inhibitor
CYP2D6 substrate & inhibitor
CYP3A4 inhibitor

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12
Q

fluvoxamine

A

CYP2C19 inhibitor

CYP3A4 inhibitor

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13
Q

isoniazid

A

CYP2C19 inhibitor

CYP3A4 inhibitor

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14
Q

omeprazole

A

CYP2C19 substrate & inhibitor

CYP3A4 substrate

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15
Q

carbamazepine

A

CYP2C19 inducer

CYP3A4 substrate & inducer

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16
Q

phenobarbital

A

CYP2C19 inducer

CYP3A4 inducer

17
Q

rifampin

A

CYP2C19 inducer

CYP3A4 inducer

18
Q

St. John’ s wort

A

CYP2C19 inducer

CYP3A4 inducer

19
Q

aripiprazole

A

CYP2D6 substrate

CYP3A4 substrate

20
Q

brexpiprazole

A

CYP2D6 substrate

CYP3A4 substrate

21
Q

dextromethorphan

A

CYP2D6 substrate

CYP3A4 substrate

22
Q

haloperidol

A

CYP2D6 substrate & inhibitor

CYP3A4 substrate

23
Q

iloperidone

A

CYP2D6 substrate

CYP3A4 substrate

24
Q

tramadol

A

CYP2D6 substrate

CYP3A4 substrate

25
Q

venlafaxine

A

CYP2D6 substrate

CYP3A4 substrate

26
Q

amiodarone

A

CYP2D6 substrate

CYP3A4 substrate & inhibitor

27
Q

ritonavir

A

CYP2D6 inhibitor

CYP3A4 substrate & inhibitor & inducer

Shared Enzymes (3 decks)

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