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Substrates Flashcards

1
Q

imipramine is a substrate of… (2)

A

CYP1A2, CYP2D6

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2
Q

theophylline is a substrate of…

A

CYP1A2, CYP2E1

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3
Q

chlorpromazine is a substrate of…

A

CYP2D6

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4
Q

escitalopram is a substrate of… (3)

A

CYP2C19, CYP2D6, CYP3A4

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5
Q

efavirenz is a substrate of…

A

CYP3A4

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6
Q

quetiapine is a substrate of…

A

CYP3A4

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7
Q

oxycodone is a substrate of…

A

CYP2D6

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8
Q

risperidone is a substrate of…

A

CYP2D6

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9
Q

diclofenac is a substrate of…

A

CYP2C9

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10
Q

warfarin is a substrate of… (3)

A

CYP1A2, CYP2C9, CYP2C19

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11
Q

dexamethasone is a substrate of…

A

CYP3A4

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12
Q

labetalol is a substrate of…

A

CYP2C19

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13
Q

ibuprofen is a substrate of…

A

CYP2C9

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14
Q

methadone is a substrate of… (2)

A

CYP2B6, CYP3A4

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15
Q

clopidogrel is a substrate of… (3)

A

CYP2C9, CYP2C19, CYP3A4

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16
Q

venlafaxine is a substrate of… (4)

A

CYP2C9, CYP2C19, CYP2D6, CYP3A4

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17
Q

paroxetine is a substrate of…

A

CYP2D6

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18
Q

suvorexant is a substrate of… (2)

A

CYP2C19, CYP3A4

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19
Q

cariprazine is a substrate of… (2)

A

CYP2D6, CYP3A4

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20
Q

alprazolam is a substrate of…

A

CYP3A4

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21
Q

clomipramine is a substrate of… (2)

A

CYP1A2, CYP2D6

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22
Q

codeine is a substrate of… (2)

A

CYP2D6, CYP3A4

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23
Q

riluzole is a substrate of…

A

CYP1A2

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24
Q

dextromethorphan is a substrate of… (2)

A

CYP2D6, CYP3A4

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25
Q

perphenazine is a substrate of…

A

CYP2D6

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26
Q

trazodone is a substrate of…

A

CYP3A4

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27
Q

ziprasidone is a substrate of…

A

CYP3A4

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28
Q

desipramine is a substrate of…

A

CYP2D6

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29
Q

clomipramine is a substrate of… (2)

A

CYP1A2, CYP2D6

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30
Q

brexpiprazole is a substrate of… (2)

A

CYP2D6, CYP3A4

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31
Q

zaleplon is a substrate of…

A

CYP3A4

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32
Q

ethanol is a substrate of…

A

CYP2E1

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33
Q

amlodipine is a substrate of…

A

CYP3A4

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34
Q

buspirone is a substrate of…

A

CYP3A4

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35
Q

amphetamine is a substrate of…

A

CYP2D6

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36
Q

fluvoxamine is a substrate of… (2)

A

CYP1A2, CYP2D6

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37
Q

meperidine is a substrate of…

A

CYP2B6

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38
Q

tramadol is a substrate of… (3)

A

CYP2B6, CYP2D6, CYP3A4

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39
Q

tasimelteon is a substrate of…

A

CYP1A2

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40
Q

duloxetine is a substrate of… (2)

A

CYP1A2, CYP2D6

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41
Q

carvedilol is a substrate of…

A

CYP2D6

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42
Q

triamterene is a substrate of…

A

CYP1A2

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43
Q

ropivacaine is a substrate of…

44
Q

progesterone is a substrate of… (2)

A

CYP2C19, CYP3A4

45
Q

metoprolol is a substrate of…

46
Q

sildenafil is a substrate of…

47
Q

carbamazepine is a substrate of…

48
Q

glyburide is a substrate of…

49
Q

erythromycin is a substrate of…

50
Q

valproic acid is a substrate of…

51
Q

glimepiride is a substrate of…

52
Q

losartan is a substrate of…

53
Q

propranolol is a substrate of… (4)

A

CYP1A2, CYP2C19, CYP2D6, CYP3A4

54
Q

doxepin is a substrate of… (5)

A

CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4

55
Q

verapamil is a substrate of… (2)

A

CYP1A2, CYP3A4

56
Q

nortriptyline is a substrate of…

57
Q

clarithromycin is a substrate of…

58
Q

pimavanserin is a substrate of… (2)

A

CYP2D6, CYP3A4

59
Q

atorvastatin is a substrate of…

60
Q

aripiprazole is a substrate of… (2)

A

CYP2D6, CYP3A4

61
Q

phenytoin is a substrate of… (2)

A

CYP2C9, CYP2C19

62
Q

tizanidine is a substrate of…

63
Q

valbenazine is a substrate of… (2)

A

CYP2D6, CYP3A4

64
Q

celecoxib is a substrate of…

65
Q

caffeine is a substrate of…

66
Q

fluoxetine is a substrate of… (2)

A

CYP2C9, CYP2D6

67
Q

zolmitriptan is a substrate of…

68
Q

lansoprazole is a substrate of… (2)

A

CYP2C19, CYP3A4

69
Q

ketamine is a substrate of…

70
Q

glipizide is a substrate of…

71
Q

metoclopramide is a substrate of…

72
Q

tamoxifen is a substrate of… (3)

A

CYP2C9, CYP2D6, CYP3A4

73
Q

acetaminophen is a substrate of…

74
Q

cyclobenzaprine is a substrate of…

75
Q

imipramine is a substrate of… (2)

A

CYP1A2, CYP2D6

76
Q

propofol is a substrate of…

77
Q

theophylline is a substrate of… (2)

A

CYP1A2, CYP2E1

78
Q

zolpidem is a substrate of…

79
Q

bupropion is a substrate of…

80
Q

hydrocortisone is a substrate of…

81
Q

donepezil is a substrate of…

82
Q

omeprazole is a substrate of… (2)

A

CYP2C19, CYP3A4

83
Q

estradiol is a substrate of…

A

CYP1A2, CYP3A4

84
Q

thioridazine is a substrate of…

85
Q

ondansetron is a substrate of… (3)

A

CYP1A2, CYP2D6, CYP3A4

86
Q

diazepam is a substrate of… (2)

A

CYP2C19, CYP3A4

87
Q

pimozide is a substrate of…

88
Q

primidone is a substrate of…

89
Q

haloperidol is a substrate of… (3)

A

CYP1A2, CYP2D6, CYP3A4

90
Q

cocaine is a substrate of…

91
Q

promethazine is a substrate of…

92
Q

fentanyl is a substrate of…

93
Q

clonidine is a substrate of…

94
Q

risperidone is a substrate of… (2)

95
Q

simvastatin is a substrate of…

96
Q

clozapine is a substrate of…

97
Q

pantoprazole is a substrate of… (2)

A

CYP2C19, CYP3A4

98
Q

citalopram is a substrate of… (3)

A

CYP2C19, CYP2D6, CYP3A4

99
Q

selegeline is a substrate of…

100
Q

amitriptyline is a substrate of… (5)

A

CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4

101
Q

voriconazole is a substrate of… (2)

A

CYP2C19, CYP3A4

102
Q

finasteride is a substrate of…

103
Q

deutetrabenazine is a substrate of…

104
Q

moclobemide is a substrate of…

105
Q

tacrin is a substrate of…

106
Q

meloxicam is a substrate of…

107
Q

olanzapine is a substrate of…

CYP450 (3 decks)

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