Substitution and Elimination Reactions

Question 1

Primary Alkyl Halides

Answer 1

Strong Base, Weak Nucleophile: E2

Everything else is SN2

Question 2

Secondary Alkyl Halides

Answer 2

Strong Base, Weak or Good Nucleophile: E2

Good Nucleophile, Weak Base: SN2

Weak Nucleophile and Weak Base: SN2 or if allylic or benzyllic position E1

Question 3

Tertiary Alkyl Halides

Answer 3

Good Nucleophile, Weak Base: SN1 or E1

Strong Base, Good or Weak Nucleophile: E2

Weak Nulceophile, Weak Base: SN1 at low temps, and E1 at high

Question 4

Good Nucleophiles

Answer 4

^-OH, MeO^-, RO^-(primary alkyl), NH₂^-, RNH^-(primary alkyl) RS^-, Cl^-, Br^-, I^-

Question 5

Strong Bases

Answer 5

^-OH, all RO^-, all RNH^-, H^-