Substance Use Disorders Flashcards
What are the C’s of Addiction?
-
Craving/Compulsion to seek and take
- craving=cant stop thining about it/get it out of their mind; pt may not label it as craving
- Use in spite of possible or actual Consequences
- Loss of Control in limiting intake
- (also Chronicity sometimes counted as C)
DSM-5
- main changes from DSM-4:
- abuse
- +craving
- -Legal problems
- sum: substance use d/o
Addiction Cycle (3 stages)
- useful for pharm and psychosocial tx
- some tx can be used at diff levels-important to know which level you are trying to target
- depression or hypomaniac will often resolve once withdrawal is over
- three main steps
- the list at each arrow stage=tx for that particular step
Animal Models of Addiction
- study nature of addiction
- examine underlying dz
- test tx
- conditioned place preference
-
condtioned place aversion
- ex: hospital-no possitive association with it because thats where they fo through withdrawal
Animal-Bing, Intoxication
- oral and iv drug self-administration
- conditioned place preference
Animal-Withdrawal, Negative Affect
- conditioned place aversion
- anxiogenic responses
- elevated plus maze
- defensive burying
- maze-enclosed spaces=less exposed, burying to avoid neg stimuli
- negative motions-anxiety
Craving, Preoccupation, Anticipation
- drug-induced reinstatement
- stress-induced reinstatement
- cue-induced reinstatement
- ex: stopping by liquor store on way to groceries; need to avoid ppl, places, things (avoid trigger nouns)
“Addicted” animals
- escalation in self-administration
- withdrawal-induced drug taking
- select lines of drug-preferring animals
- drug taking in spite of consequences
- relapse
- **check feelings for pt, may not like them
What are the (4) models of addiction
- Moral model
- learning model
- self-medication model
- ***disease model
Moral Model of Addiction
- only model for most of hx and still most pop
- causes:
- moral weakness/lack of willpower
- tx: punishment or spiritual
- GOOD: gives pt responsibility
- BADL blaming pt
Learning Model of Addiction
- thoughts lead to emotions which lead to behabiors
- caused by learned maladaptive habits
- treat:
- learn triggers
- learn new cognitions
- learn new behaviors
- stimulus control
- response prevention
- coping skills
- CBT/relapse prevention employ this model in pt
Self-Medication Model of Addiction
- physiological and cognitive
- cognition may become distorderd
- external locus of control-blame someone else for all their problems
- takes it out of their hands
- somtimes the drugs will actually make the mental illness worse
**Disease Model of Addiction**
- caused by dz
- important 3-step therapy:
- pharmacotherapy
- 12-step referral
- psychosocial tx
- genetics/environment
- educate family members about exposure, etc
- dont necessarily have that second step of psychological symptoms en route to substance use (unlike self-med model that has 3 steps)
ASAM definition of Addiction
Addiction is a primary, chronic dz of brain reward, motivation, memory and related circuitry.
Dysfxn in these circuits leads to characteristic biological, psychological, social and spiritual manifestations.
This is reflected in an indiv pathologically pursuing reward and/or relief by substance use and other behaviors…”
Addiction as Chronic Disease
- For some people best viewed as chronic, severe, recurrent disease
- Like diabetes, HTN, asthma
- Similarities
- Behavioral factors associated with onset
- Genetic influences
- Rates of tx compliance (30-50%)
- Rates of relapse (30-70%)
- Worsening and potentially fatal if untx
- Those in tx:
- 20+ years
- Brief episodes of tx and/or incarceration
- Gradually longer periods of abstinence
- **look at long-term sobriety
Substance Use Epidemiology
- 8.7% used illicit drugs in past month (22 million)
- 52% drank alcohol (133 million)
- 23% binged (58 million)
- 6.2% heavy alcohol use (16 million)
- 26.5% population used tobacco (68.2 million) in 2011
- Decrease from 30.4% in 2002
10,50,25,5,25,30
Definition of binge and heavy-drinking
- Binge = 5+ drinks/day
- Heavy drinking = 5+binges/month
Substance Dependence or Abuse in the past yr; ppl 12 and older
- 20.6M total (~8%) [in 2011-last bar]
- 14M alcohol (~5.4%)
- 3.9M drugs (~1.5%)
- 2.6M both (~1%)
Specific Illicit Drug Dependence or *ABUSE* in past yr, ppl 12 or older (2011)
- when perscribed meds are abused they are not purchased from a dealer. often theyre real scripts stolen from a family/friend
- note:sedatives=BX
- look at the levels of MJ and pain relievers
Early onset impact
- the earlier the exposure, the higher likelihood of alcohol disorder in adulthood
- ***early onset of substance use is a MAJOR RF for subseqent onset of subtace use disorder
- alcohol and MJ (in tne image)