SUBSTANCE MISUSE Flashcards

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1
Q

What alcohol related conditions might lead someone turning up at A&E?

A
Alcohol related injury
Alcohol withdrawal
Alcohol overdose
Suicide attempts precipitated by alcohol
MI
Liver failure
Oesophageal bleeds (varicele bleeds) due to vomiting
Varicose veins (portal hypertension)
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2
Q

Are you likely to become dependant on alcohol if you binge drink every Friday and Saturday?

A

No. You pretty much have to drink an amount everyday.

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3
Q

Which organs become tolerant to alcohol?

A

Liver and the brain. Those who are alcohol dependant rely on it to function cognitively.

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4
Q

What the signs and symptoms of alcohol withdrawal?

A
Nausea
Retching
Tremor
Tachycardia
Affected gait
Seizures
DT (deliruim tremens) - acute confusion, hallucinations (insects on the floor, snakes on the curtains), intense fear often accompanies the hallucination
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5
Q

Why are delirium tremens common on the ward?

A

Because alcoholics are often admitted to the ward for other reasons, but they have no access to alcohol on the ward.

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6
Q

When do delirium tremens normally start?

A

Normally not until 72 hours after the last drink.

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7
Q

When do seizures due to alcohol withdrawal usually occur?

A

About 36 hours after their last drink.

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8
Q

Why are alcoholics more likely to develop varicose veins?

A

Portal hypertension from liver failure and cirrhosis.

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9
Q

Why might alcoholics be more likely to bleed?

A

Liver failure due to cirrhosis therefore not able to make enough clotting factors.

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10
Q

What is Wernicke’s encephalopathy and why are alcoholics more likely to develop it?

A

It is a loss of short term memory caused by thiamine deficiency. Alcoholics often neglect eating and therefore end up with a deficiency in any number of vital vitamin and amino acids.

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11
Q

What is Korsakoff’s syndrome?

A

It is the permanent form of Wernicke’s encephalopathy (loss of short term memory), also caused by thiamine deficiency.

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12
Q

What are questions that you would want to ask someone who you suspect might be alcohol dependant?

A

How much do you drink?
How many times a week?
What happens if you don’t drink during a day?
Do you ever drink in the morning?

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13
Q

What signs might be seen during a physical examination of someone who is alcohol dependant?

A
Peripheral neuropathy
Ascites
Bruising
Gynecomastia
Hepatomegaly
Splenomegaly
Lack of coordination
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14
Q

What might blood tests reveal in an alcoholic?

A
Raised LFTs
Raised gamma GT
Raised AST
Raised IgA
Raised bilirubin
Abnormal clotting factor levels
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15
Q

What drug might you give an alcohol dependant individual to help them with alcohol withdrawal?

A

Chlordiazepoxide

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16
Q

What does GHB stand for?

A

Gamma-hydroxybutyrate

17
Q

Is mephedrone a stimulant or a depressant?

A

Stimulant

18
Q

What is crystal meth?

A

A long acting amphetamine

19
Q

What are the common psychological effects of crystal meth?

A
Psychosis
Paranoia
Anxiety
Depression
Violence
Suicide
20
Q

What are the withdrawal signs and symptoms of heroine and other opiates?

A
Sweats (cold and clammy), 
Goosebumps 
Nausea
Retching
Abdominal pain
Diarrhoea
Muscle cramps and spasms
Yawning
Pupil dilatation
Lacrimation
Rhinorrhoea
Tachycardia
21
Q

What is the serious consequence of heroine overdose?

A

Death through respiratory depression

22
Q

What is the antidote to heroine?

A

Naloxone

23
Q

What is the most common blood borne virus in intravenous drug users in the UK?

A

Hepatitis C

24
Q

What percent of intravenous drug users have HIV in the UK?

A

Less than 1%