Substance Abuse 1 Flashcards
What is a drug?
Medicine or other substance which has a physiological effect when ingested or otherwise introduced into the body
Which group are most likely to misuse drugs?
Age 16-24
What percentage of people have alcohol dependence?
4%
What is a substance use disorder?
cluster of cognitive, behavioural, and physiological symptoms indicating that the individual continues using the substance despite significant substance-related problems
What is addiction?
Chronic, primary, neurobiological condition influenced by genetic, psychosocial and environmental factors
What are the risk factors for drug misuse and addiction?
Genetics- men more likely
Socioeconomic
Environmental:
Home, family, friends using drugs
Low-self esteem
Stress
Easy access to drugs
Peer pressure
Mental health problems
Early exposure
Physical and sexual abuse
Trauma
Homelessness
What are the steps in the addiction cycle for recreational drugs?
Acute reinforcement/social drug taking
Escalating, binging, compulsive use
Dependence
Withdrawal
Protracted withdrawal
Recovery?
What is the initiation and progression of drug use most associated with?
Initiation- social and environmental factors
Progression- neurobiological factors
What are the steps in the pattern of addiction for opioids?
Intense initial intoxication
Development of tolerance
Escalation in intake
Profound dysphoria, physical discomfort and somatic withdrawal signs during abstinence
What is the addiction pattern for alcohol?
Initial intoxication less than opiods
Binges
Severe emotional and somatic withdrawal syndrome
Intense craving for drug often driven by negative emotional states but also positive
What areas of the brain are associated with the reward pathway?
Ventral Tegmental Area
Nucleus Accumbens
Prefrontal cortex
What occurs in the reward pathway?
Activated by rewarding stimulus (food, water, sex)
-> information travels from the VTA then Nucleus accumbens then prefrontal cortex
-> dopamine mediated transmission allows feeling of pleasure
What are the effects of different neurotransmitters on how we feel?
Increased dopamine- euphoria
Increased serotonin- increased contentment
What are the elements in the psychodynamic theory of addiction?
2 critical
-> disordered emotions
-> disordered self- care
2 contributory
-> disordered self-esteem
-> disordered relationships
What happens upon chronic exposure to drugs?
Reduced sensitivity of brain to reward system