Study ?S Flashcards

1
Q

Which ICS/LABA is NOT FDA approved for COPD?

A

Airduo (salemeterol 14mcg) and Dulera (mometasone/formoterol 5mcg)

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2
Q

COPD - The LABA or LAMA is not working what do you do?

A

LABA/LAMA

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3
Q

COPD - The LABA/ICS is not working, what do you do?

A

Triple therapy or increase the dose or switch to LABA/LAMA

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4
Q

COPD Exacerbation and on triple therapy - what do you do?

A

Add roflumilast if mucous bronchitis and FEV <50% - biologics - zmax for smokers

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5
Q

GOLD Guidelines Group A Tx

A

bronchodilator, short or long acting, long acting preferred unless seldom SOB

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6
Q

GOLD Guidelines Group B Tx

A

LABA or LAMA (LAMA better)

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7
Q

GOLD Guidelines Group E Tx

A

LABA/LAMA or Triple therapy if eosinophils >300

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8
Q

GOLD Guidelines Group A exacerbations, mMRC, and CAT scores

A

0 or 1 exacerbations, 0 hospitalizations, mMRC <2, CAT <10

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9
Q

GOLD Guidelines Group B exacerbations, mMRC, and CAT scores

A

0 or 1 exacerbations, 0 hospitalizations, mMRC>2 or CAT >10

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10
Q

GOLD Guidelines Group E exacerbations, mMRC, and CAT scores

A

> 2 exacerbations, mMRC and CAT are all irrelevant, treated the same

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11
Q

IL-4 Antagonist for asthma

A

Dupixent (Dupilumab)

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12
Q

IL-5 Antagonists for asthma

A

Benralizumab
Reslizumab
Mepolizumab

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13
Q

anti-TSLR for asthma

A

Tezepelumab (Tezspire)

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14
Q

Asthma Step 1 Tx

A

Symbicort PRN

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15
Q

Asthma Step 2 Tx

A

Symbicort PRN (could be scheduled)

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16
Q

Asthma Step 3 Tx

A

Low-dose Symbicort and PRN

17
Q

Asthma Step 4 Tx

A

Med-dose Symbicort and PRN

18
Q

Asthma Step 5 Tx

A

High Dose Symbicort
Triple Therapy
Immunologics

19
Q

Only LAMA approved for asthma >12

A

Spiriva Respimat

20
Q

Inhaler contraindicated in milk allergy

A

Fluticasone Arnuity Ellipta

21
Q

Asthma Control Class… Frequency of Symptoms

A

Mild - <2 days/wk
Mild Persistent - 2-5 days/wk
Mod Persistent - >5 days but not daily
Severe Persistent - throughout the day

22
Q

Asthma Control Class…
Nighttime Awakenings

A

Mild - <2/mo
Mild Persistent - 2-4 mo
Mod Persistent - >4/mo
Severe Persistent - nightly

23
Q

Asthma Control Class…
Activity Interference

A

Mild - none
Mild Persistent - slight
Mod Persistent - some
Severe Persistent - a lot

24
Q

Asthma Control Class…
OCS use

A

Mild - 0 or 1
Persistent - at least twice

25
Q

Mild Asthma Tx

A

SMART - Symbicort PRN or SABA PRN based on age

26
Q

Mild Persistent Asthma Tx

A

Symbicort PRN (could schedule)
SABA PRN, schedule ICS

27
Q

Severe Persistent Asthma Tx

A

High Dose ICS-LABA
Triple Therapy
OCS

28
Q

Moderate Persistent Asthma Tx

A

Symbicort low dose scheduled and PRN

ICS med dose and SABA PRN

Possible OCS