Study Questions - Pharmacology

Question 1

This is the process of absorption, distribution, metabolism and excretion.

Answer 1

Pharmacokinetics

Question 2

This is the most important organ for drug excretion

Answer 2

The kidneys

Question 3

These (2) are the largest effect a drug can produce and the amount we must give to elicit the effect

Answer 3

maximal efficacy and relative potency (dose-response relationship)

Question 4

This interaction occurs when one drug alters the effect of another

Answer 4

What is pharmacokinetic reaction

Question 5

Most biotransformation occurs in this organ

Answer 5

the liver

Question 6

These products do not require FDA approval

Answer 6

dietary supplements

Question 7

the nurse should teach a patient prescribed statins that taking it with grapefruit juice can cause this problem

Answer 7

toxicity (excess drug levels in the body)

Question 8

drug- food interactions can produce these effects

Answer 8

toxicity and therapeutic failure

Question 9

This is the measure of a drugs safety

Answer 9

therapeutic index

Question 10

the nurse knows that this process will be altered in an adult with liver disease

Answer 10

biotransformation or metabolism

Question 11

The nurse recognizes this as the reason for an order that adds prn opiate dosing and increases standing opiate dosing in a terminal cancer patient

Answer 11

tolerance

Question 12

this is a criteria for potentially inappropriate medication use in older adults

Answer 12

Beers Criteria

Question 13

the study of how genetic variations can produce different drug effects

Answer 13

pharmacogenetics

Question 14

only neurotransmitter that activates B2 adrenergic receptors

Answer 14

epinephrine

Question 15

the nurse prepares to administer ketorolac to an 83 yr old patient. what finding would warrant withholding the medication and contacting the prescriber ?

Answer 15

history of a GI bleed

Question 16

this is a priority nursing action to promote excretion of most anesthetics after inpatient surgery

Answer 16

IV hydration

Question 17

the nurse knows that this type of agonist results in bronchodilation

Answer 17

beta 2 agonist

Question 18

the nurse would question an order for an anticholinergic medication prescribed for a patient with what genitourinary problem

Answer 18

urinary retention

Question 19

these are classified by chemical names, generic names and trade names

Answer 19

drug names

Question 20

this is a noxious, unintended effect that occur at normal doses

Answer 20

adverse drug effect

Question 21

This drug type is effective, safe and selective

Answer 21

Ideal Drug

Question 22

these are molecules that activate receptors

Answer 22

agonists

Question 23

this is a decreased response to a drug as a result of repeated drug administrations

Answer 23

tolerance

Question 24

this is the study of what drugs do to the body and how they do it

Answer 24

pharmacodynamics

Question 25

taking two medications at the same time can affect this process in the body

Answer 25

pharmacokinetic process (ADME)

Question 26

this is the rapid hepatic inactivation of certain oral drugs

Answer 26

first- pass effect

Question 27

this is the time required for the amount of drug in the body to decrease by 50%

Answer 27

half life

Question 28

these produce their effects by preventing receptor activation

Answer 28

antagonists

Question 29

a patient is prescribed clopidogrel to prevent blood clots after a myocardial infarction. The patient self prescribes omeprazole (OTC) for heartburn. Omeprazole inhibits the efficacy of clopidogrel. It is priority to teach the patient to report what effect?

Answer 29

Shortness of breath or chest pain