Study Design Flashcards
What is the most appropriate study design to assess treatment/intervention?
Randomised control trial
What is meant by a randomised control trial?
Experimental study design
Individuals or groups are randomly assigned to either a control or interventional group
What level of evidence is a randomised control trial?
1b
What is the most appropriate study design to assess prognosis?
Cohort study
What are three different types of observational study?
Case Studies/Case Reports
Case-Control Study
Cohort Study
What are the limitations of case reports/case studies?
They merely describe an interesting case
Weakest in the hierarchy of evidence
They have no control group for comparison
They do not undergo statistical analysis
What is meant by a case-control study?
Observational study
A sample of diseased individuals is compared with disease-free people by examining them retrospectively for the presence or absence of hypothesised risk factors
What is meant by a cohort study?
Observational study
A cohort of disease-free individuals are followed forward over time for the appearance of a disease
The cohort may share a common exposure or risk factor for a certain disease
What is meant by a double blind RCT?
Neither the participants nor the researcher are aware at the time of the study as to which participants are receiving the intervention
What is meant by a single-blind RCT?
Only the researcher is aware at the time of the study as t which participants are receiving the intervention
What is meant by an open/non-blinded RCT?
Both the researchers and the subjects are aware of the intervention in question
What is the most appropriate study design to assess diagnostic tests?
Cross-sectional study
What level of evidence is from a panel of experts
4
