Study Flashcards
1
Q
Reactive arthritis script
A
A few weeks following GI or GU infection, pt develops: - asymmetric oligoarthritis - achilles enthesitis - uveitis - urethritis - dactylitis - keratoderma blennorrhagica (peeling soles of feet) - circinate balanitis (serpiginous dermatitis of the glans)
2
Q
Extrapyramidal symptoms Bonus: what med can reverse EPS in cases of anticholinergic overdose?
A
EPS: - akathisia (motor restlessness) - parkinsonism (mask-like facies, resting tremor, cogwheel rigidity, shuffling gait, and psychomotor retardation [bradykinesia]) - dystonias physostigmine
3
Q
congenital toxoplpasmosis: RF, CF, dx, tx
A
RF/source:
- cat feces
- undercooked meat
- unwashed vegetables
CF:
- macrocephaly, hydrocephalus
- chorioretinitis [on ophtho exam]
- diffuse intracranial calcifications [on CT]
- non-specific cong. infection ssx (eg growth restriction, jaundice, HSM, blueberry muffin rash, hearing impairment)
dx:
- serology (toxo IgG, IgM, IgA in mom and baby)
- LP (protein, pleocytosis, toxo PCR)
tx:
- pyrimethamine
- 2mg/kg qd x2d, then:
- 1mg/kg qd x6 MONTHS, then:
- 1mg/kg MWF x6 MONTHS
- sulfadiazine
- 50mg/kg BID x1 YEAR
- folinic acid (leucovorin)
- 10mg MWF x1 YEAR + 1 wk after pyrimthamine therapy is terminated
- Weigh infant weekly to adjust dosing
4
Q
High Risk & Low Risk Abx for C. diffe
A
High Risk
- Fluoroquinolones
- Clindamycin
- 3/4th gen cephalosporins
- carbapenems
- monobactams
Low Risk
- Bactrim
- Macrolides
- Tetracyclines
- Aminoglycosides
5
Q
Clinical features of CF
A
- Meconium ileus in newborns
- Recurrent sinopulmonary infections
- Pancreatic insufficiency & diabetes
- Male infertility
