Structure Of Skeletal Muscle Flashcards

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1
Q

What are the three types of muscle in body? And where they found

A

Cardiac muscle - heart

Smooth muscle- walls of blood vessels and gut

Skeletal muscle - it is attached to bone and acts involuntary, conscious control

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2
Q

What are muscles made up of

A

Millions of tiny muscle fibres called myofibrils

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3
Q

What’s within the sarcoplasm

A

Large concentration of mitochondria and endoplasmic reticulum

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4
Q

What do the muscle fibres share when separate cells have become fused together into muscle fibres

A

They share nuclei and cytoplasm, called sarcoplasm

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5
Q

What are the I bands ?

A

The light bands. They appear lighter because the thick and thin filaments do not overlap in this region

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6
Q

What are the A bands

A

The dark bands. They appear darker because the thick and thin filaments overlap in this region

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7
Q

What’s at the centre of each A band?

A

A lighter coloured region called the H zone

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8
Q

What’s at the centre of each I band

A

The Z line

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9
Q

What’s the distance between adjacent Z lines

A

A sacromere

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10
Q

What happens when a muscle contract to the sacromere

A

It shortens and the pattern of light and dark bands changes

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11
Q

What is tropomyosin

A

An important protein found in muscles

Which forms a fibrous strand around the actin filament

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12
Q

What are slow twitch fibres

A

These contract mite slowly than fast twitch fibres and provide less powerful contractions but over a longer period

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13
Q

What type of work are slow twitch fibres adapted for

A

Endurance work such as a marathon

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14
Q

How are they adapted for aerobic respiration to avoid build up of lactic acid

A

Large myoglobin stores ( stores oxygen)

Rich supply of blood vessels to deliver oxygen and glucose for aerobic respiration

Numerous mitochondria to produce ATP

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15
Q

What are fast twitch fibres

A

These contract more rapidly and produce powerful contractions but only for a short period

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16
Q

What are fast twitch fibres adapted for

A

Intense exercise such as weight lifting

17
Q

How are fast twitch fibres adapted to their role

A

They have thicker and more numerous myosin filaments

A high concentration of glucose

A high concentration of enzymes involved in anaerobic respiration which provides ATP rapidly

A store of phosphocreatine, a molecule that can rapidly generate ATP from ADP in anaerobic conditions and so provide energy for muscle contractions

18
Q

What is a neuromuscular junction

A

Is the point where a motor neurone meets a skeletal muscle fibre

19
Q

How is the control over he force exerted controlled

A

As all muscle fibres supplied by w single motor neurone act together as a single functional unit (motor unit)

If only a slight force is needed, only a few units are stimulated

If a greater force is required, a larger number of units are stimulated

20
Q

What happens before muscle contraction when a nerve impulse is received at the neuromuscular junction

A

The synaptic vesicles fuse with the presynaptic membrane and release their acetylcholine.

The acetylcholine diffuses to the post synaptic membrane (membrane of muscle fibre), altering its permeability to sodium ions, which enter rapidly, depolarising the membrane.

The acetylcholine is broken down by acetylcholinesterase to ensure that the muscle is not over stimulated

The resulting choline and acetyl (etanoic acid) diffuse back into the neurone, where they are recombined to form acetylcholine using energy provided by mitochondria found there

21
Q

How is a neuromuscular junction similar to a cholinergic synapse

A

Have neurotransmitters that are transported by diffusion

Have receptors, that on binding with the neurotransmitter, cause an influx of sodium ions

Use a sodium potassium pump to repolarise the axon

Use enzymes to breakdown the neurotransmitter

22
Q

What are the differences between a neuromuscular junction and cholinergic synapse

A

N- only excitatory
C- may be excitatory or inhibitory

N- only links neurones to muscles
C- links neurones to neurones, or neurones to other effect organs

N- only motor neurones involved
C- motor, sensory and intermediate neurones may be involved

N- the action potential ends here
C- a new action potential may be produced along another neurone

N- acetylcholine binds to receptors on membrane muscle fibre
C- acetylcholine binds to receptors on membrane post synaptic neurone

23
Q

What are the two types of protein filament

A

Actin - thinner and consists of two strands twisted around one another

Myosin - which is thicker and consists of long rod shaped tails with bulbous heads that project to the side