Structure of DNA and RNA Flashcards
what type of bonds join nucleotides together
covalent bonds join phosphates to sugars in nucleotides and along the side backbone
hydrogen bonds join the bases together across the double stranded DNA
how do DNA and RNA differ
number of strands (2 vs 1) base composition (RNA had U instead of T) type of pentose sugar (DNA has deoxyribose and RNA has ribose)
what are nitrogenous bases
pyrimidines (smaller): cytosine/uracil/thymine
purines (larger): guanine/alanine
how are DNA strands drawn
antiparallel (5 to 3 and 3 to 5)
complementary base pairing
hydrogen bonds drawn as dotted lines
what is the function of a nucleosome
nucleosomes are only in eukaryotic cells
they have a core of 8 histones
DNA is wrapped around the nucleosomes (supercoiling)
what did hershey and chase prove
DNA is the genetic material of viruses
what did crick and watson create
created the 3D model of the double helix DNA
what did rosalind franklin investigate
franklin studied DNA by X-Ray diffraction to calculate dimensions of the DNA helix
watson and crick stole her work to build their model and then won a Nobel Prize
what is a nucleotide
building blocks of nucleic acids
contains pentose sugar (ribose/deoxyribose)
-phosphate group
nitrogenous base (A/T/G/C/U)
(adenine/thymine/guanine/cytosine/uracil)
what is the importance of dna
codes for proteins which in turn control cell processes including the production of chemicals in specialised cells
- permanently stores information about which enzymes need to be made
- organises information so different cells can use the parts they need and ignore the rest
- contained within chromosomes (found in nucleus) but require rna to be used