Structure of DNA and RNA Flashcards

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1
Q

what type of bonds join nucleotides together

A

covalent bonds join phosphates to sugars in nucleotides and along the side backbone
hydrogen bonds join the bases together across the double stranded DNA

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2
Q

how do DNA and RNA differ

A
number of strands (2 vs 1)
base composition (RNA had U instead of T)
type of pentose sugar (DNA has deoxyribose and RNA has ribose)
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3
Q

what are nitrogenous bases

A

pyrimidines (smaller): cytosine/uracil/thymine

purines (larger): guanine/alanine

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4
Q

how are DNA strands drawn

A

antiparallel (5 to 3 and 3 to 5)
complementary base pairing
hydrogen bonds drawn as dotted lines

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5
Q

what is the function of a nucleosome

A

nucleosomes are only in eukaryotic cells
they have a core of 8 histones
DNA is wrapped around the nucleosomes (supercoiling)

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6
Q

what did hershey and chase prove

A

DNA is the genetic material of viruses

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7
Q

what did crick and watson create

A

created the 3D model of the double helix DNA

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8
Q

what did rosalind franklin investigate

A

franklin studied DNA by X-Ray diffraction to calculate dimensions of the DNA helix
watson and crick stole her work to build their model and then won a Nobel Prize

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9
Q

what is a nucleotide

A

building blocks of nucleic acids
contains pentose sugar (ribose/deoxyribose)
-phosphate group
nitrogenous base (A/T/G/C/U)
(adenine/thymine/guanine/cytosine/uracil)

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10
Q

what is the importance of dna

A

codes for proteins which in turn control cell processes including the production of chemicals in specialised cells

  • permanently stores information about which enzymes need to be made
  • organises information so different cells can use the parts they need and ignore the rest
  • contained within chromosomes (found in nucleus) but require rna to be used
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