STRUCTURE OF A NEURON Flashcards
It is the neuron’s control center, containing the nucleus and other organelles. it process incoming signals and maintains the neurons health
CELL BODY (SOMA)
contains the cell genetic material (DNA)
NUCLEUS
includes various organelles such as mitochondria (energy production) ribosomes (protein synthesis)
CYTOPLASM
are branching extensions that receive signals from other neurons. they conduct electrical message to the cell body.
DENDRITES
carries electrical impulses away from the cell body to other neuron, muscles or organelles
AXON
The cone-shaped region where the axon joins the cell body. it is the site where action potential are initiated.
AXON HILLOCK
A fatty layer that covers the axon in segments. it acts as an insulator, increasing the speed of signal transmission
MYELIN SHEATH
Gaps in the myelin sheath where ion channels are concentrated, allow the action potential to jump from node to node (saltatory conduction)
NODES OF RANVIER
the end points of axon where neuron makes contact with other cells. where neurotransmitter release into synaptic cleft to communicate with other neurons or affector cells
AXON TERMINAL (SYNAPTIC BOUTONS)
It is a fluid within cells
ICF (INTRACELLULAR FLUID)
What are the 3 major ions in the ICF
POTASSIUM (K+)
PHOSPHATE (HPO4^2-) AND PROTEINS
SODIUM (Na+)
The predominant ion with a high concentration inside the cell
POTASSIUM (K+)
These are negatively charged and help balance the positive charged and help balance the positive charge of K+
PHOSPHATATE (HPO4^2-) AND PROTEINS
Present in lower concentrations compared to the extracellular fluid.
SODIUM (Na+)
the fluid outside cells, including interstitial fluid and blood plasma
ECF (EXTRACELLULAR FLUID)
Major ions in the ECF
SODIUM (NA+)
CHLORIDE (CL-)
CALCIUM (CA2+)
POTASSIUM (K+)
The predominant ion with a high concentration outside the cell.
SODIUM (NA+)
The main anion in the ECF
CHLORIDE (CL-)
Also, present in a significant amount
CALCIUM (CA2+)
present in lower concentrations compared to the intracellular fluid.
POTASSIUM (K+)
It plays a pivotal role in generating and propagating action potential
ELECTROCHEMICAL GRADIENT
This gradient is formed due to differences in the concentration of ions across the membrane. ions will naturally move from an area of higher concentration to an area of lower concentration to reach equillibrium
CHEMICAL GRADIENT
this gradient is formed due to differences in the concentration of ions across the membrane. ions are attracted to areas of opposite charge.
ELECTRICAL GRADIENT
a brief electrical impulse that travels along the axon of a neuron triggered when the membrane potential reaches a certain threshold it results in the rapid depolarization and repolarization
ACTION POTENTIAL
the stable voltage difference across a cell membrane when the neuron is not actively firing an action potential
RESTING POTENTIAL
is the movement of particles from an area of higher concentration to an area of lower
concentration.
DIFFUSION
These are proteins that create specific pathways for charged ions to pass
through the cell membrane.
ION CHANNELS
Always open, allowing ions to move down their concentration gradient.
LEAK CHANNELS
Open or close in response to specific stimuli (voltage-gated, ligand-
gated, or mechanically gated).
GATED CHANNELS
Active transport mechanisms that move ions against their concentration
gradients using ATP.
ION PUMPS
a membrane protein that actively transports sodium ions out of the neuron and potassium into the neurons
SODIUM-POTASSIUM PUMP
the process by which the membrane potential of a neuron becomes less
negative (more positive) than its resting potential. This is a critical step in the generation of an action
potential.
DEPOLARIZATION
refers to the process by which the membrane potential becomes more negative than the resting
potential.
HYPERPOLARIZATION
occurs after an action potential has been fired. During an action potential, the neuron’s
membrane potential becomes more positive (depolarization) due to the influx of sodium ions (Na+) into the cell.
REPOLARIZATION
play a crucial role in maintaining
the fidelity of neuronal signaling. These
mechanisms are essential for proper neuronal
communication and overall nervous system
function.
REFRACTORY PERIODS
This is the period immediately following the initiation of an action potential during which no
stimulus, no matter how strong, can trigger another action potential.
ABSOLUTE REFRACTORY PERIOD
period, there is a phase during which a neuron can fire another
action potential, but only in response to a stronger-than-usual stimulus.
RELATIVE REFRACTORY PERIOD
An action potential either occurs fully or not at all. Once the
threshold is reached, the action potential will propagate along the entire length of the
axon without decreasing in size.
ALL-OR-NOTHING PRINCIPLE