Structure & Function Flashcards
how much blood is in the body, and what % of body weight does it make up?
4-5 L; 8%
Functions of blood?
- carry O2, nutrients, CO2, waste, hormones
- regulate fluid balance, temp, & pH
- clotting
- immunity
blood is made out of what?
plasma & formed elements
What are the formed elements?
erythrocytes, leukocytes, and platelets
What makes up the buffy coat?
leukocytes & platelets
How much of the blood does plasma make up?
55%
What is the percent composition of plasma?
91% water, 8% protein, 1% other
What are found in the protein of plasma?
- albumin
- clotting factors
- antibodies
- complement
What are found in the other part of plasma?
- glucose
- amino acids
- vitamins
- lipids
- electrolytes
- hormones
- dissolved gases
- drugs
- wastes
Erythrocytes make up what percent of blood?
45%
how many erythrocytes are in 1mm^3 of blood?
4.5-5.5 million
What is the life span of RBCs?
90-120 days
What is the purpose of RBC’s biconcave shape
flexibility & SA for gas exchange
Compared to WBCs, RBCs lack what
nucleus & very little organelles
Purpose of hemoglobin
facilitate O2 & CO2 movement & carry H ion for buffering
RBCs cannot what
divide, do aerobic respiration, & don’t have survival abilities
What are the largest, most common, and smallest formed elements?
largest: leukocytes
common: RBCs
smallest: platelets
How many leukocytes are in 1mm^3?
5,000-10,000
what is the life span of WBCs?
9 days
What are the 2 types of WBCs?
granulocytes & agranulocytes
What are the subtypes of granulocytes?
neutrophils, basophils, & eosinophils
What is the % & purpose of neutrophils
60%, phagocytes
What is the % & purpose of basophils
<1%, fights allergies
What is the % & purpose of eosinophils
3%, eat parasites
What are the subtypes of agranulocytes?
lymphocytes & monocytes
What is the % & purpose of lymphocytes
30%, immune system
What is the % & purpose of monocytes
6%, phagocytes
Platelets are also called what
thrombocytes
How many platelets should be in 1mm^3 of blood
250,000-400,000
What is the lifespan of platelets
5-9 days
T/F: platelets are cells
false (no nuclei & no DNA)
Purpose of platelets?
clotting
define hematopoiesis
creation of all blood cells in red marrow
define hemostasis
stopping blood loss (via blood clotting usually)
What are the steps to clotting?
- prothrombinase is formed
- prothrombinase turn prothrombin –> thrombin
- Thrombin turn fibrinogen –> fibrin
- Fibrin form network of threads –> clot
What is the purpose of WBCs?
get rid of foreign materials, cellular debris, & disease
What is needed for clotting?
calcium
What % does the buffy coat make up
1%
What are the steps of hemostasis?
- vascular spasm
- platelet plug
- coagulation