Structure & Chemical Composition of Viruses Flashcards

1
Q

What is the smallest virus

A

Porcine Cirocovirus Type 1 (17nm) , followed by parvovirus (18nm)

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2
Q

What is the largest virus?

A

Pandoravirus (400nm) the step below it is the poxvirus (200nm)

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3
Q

what is pleomorphism?

A

the ability of some virus to alter their shape or size

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4
Q

What is the morphology of a virus?

A

DNA or RNA genes surrounded by a capsid, surrounded by an envelope (a bubble of fat), then molecules of protein on the envelope

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5
Q

what is a capsid?

A

the protein shell of a virus that encases / envelopes the viral nucleic acid or genome.

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6
Q

what is the capsid made up of?

A

capsomeres held together by non-covalent bonds

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7
Q

what is the basic sub-unit protein in the capsid of a virus?

A

a capsomere

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8
Q

what is a nucleocapsid?

A

Capsid + Virus nucleic acid (DNa/RNA)/genome

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9
Q

because of the interaction between the nucleic acid and capsid proteins…

A

incomplete virions (empty helical partricles) cannot form.

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10
Q

in all animal viruses the helical necleocapsid is..

A

enclosed within a lipoprotein envelope

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11
Q

naked helical necleocapsides are common among..

A

plant viruses

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12
Q

what are the two types of capsomers present in the icosahedral capsid?

A

(spherical Viruses) pentagonal capsomers at the verices (pentons) and hexagonal capsomeres making up the facets (hexons)

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13
Q

there are always ___ pentons?

A

12 (spherical virsues)

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14
Q

the number of hexons ______

A

varies with the virus group (spherical viruses)

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15
Q

what is the Trangulation number?

A

describes the relation between the number of pentagons and hexagons of the icosahedron the larger the T-number the more hexagons are present relative to pentagons

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16
Q

what is the simplest icosahedron?

A

parvovirus T=1, consists of 60 copies of the CP protein

17
Q

what is the function of the viral capsid?

A

structural symmetry, encases and protects the viral nucleic acid from enzymes, chemical and physical conditions

18
Q

slide 29

A

stoped