Structure And Mode Of Action Of A Receptor

Question 1

Define Antagonist

Answer 1

To turn ‘off’ the response by ‘blocking’ the receptor from the agonist.

Question 2

Example of Agonists

Answer 2

Morphine- Agonist bind to the receptor on a cell mimicking the actions of Endorphins.

(Endorphins inhibit the transmission of pain signals)

Question 3

Example of antagonists

Answer 3

‘Beta-blocker’ drug group. They decrease the activity of the heart by blocking the action of hormones like adrenalin.

Beta-blocker treat- Angina, Heart attacks,* Heart failure.

Drugs include- Propranolol, Atenolol, (lol drugs)

Question 4

What is a receptor

Answer 4

Receptors are large protein molecules in a cell that can be activated by the binding of a Ligand (Hormone or Drug)

Question 5

How do receptors bind with ligands

Answer 5

While numerous receptors are found in most cells, each receptor will only bind with ligands of a particular structure, much like how locks will only accept specifically shaped keys.

Question 6

Define Agonists

Answer 6

To turn ‘on’ a single cellular response by binding to the receptor, thus initiating a biochemical mechanism for change with a cell. (Causes an action)

Question 7

Where is a Receptor found

Answer 7

A Receptor is a protein molecule, usually found embedded In the plasma membrane surface of a cell.

Question 8

How do Receptors work

Answer 8

Receptors receive chemical signals from outside the cell, when such chemical signals bind to the receptor, they cause some form of cellular/tissue response.

Question 9

What is a Ligand

Answer 9

Ligand is a substance, usually a small molecule, that forms a complex (a bound of molecules)