Structure and Functions of CNS 2 Flashcards

1
Q

Degeneration of which part of brain results in Parkinsons Disease?

A

Substantia nigra- caudal midbrain

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2
Q

Where is the red nucleus? what does it do?

A

Involved in motor control, receive fibres from motor cortex, frontal lobe
Rostal midbrain

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3
Q

How is the cerebellum connected to the brainstem?

A

BY 3 pairs of fibre bundles:

Inferior, middle, superior cerebellar peduncles

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4
Q

What does cerebellum do?

A

Voluntary movement
Balance
Coordination

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5
Q

Subdivisions of Cerebellum

A

Archicerebellum-oldest part, balance
Paleocerebellum- posture, muscle tone
Neocerebellum- muscular coordination, force of movement

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6
Q

What is Nystagmus?

A

Incordination of eye movement

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7
Q

Symptoms of a cerebellar lesion

A

Intention tremor
Lower limbs (cerebellar ataxia)
Speech (dysarthria)
Eyes (nystagmus)

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8
Q

Unilateral lesion of cerebellar hemisphere

A

Symptoms on the same side of body

Ipsilateral

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9
Q

Bilateral dysfunction of cerebellar due to what?

A

Alcohol intoxication
Hypothyroidism
Inherited cerebellar degeneration/ataxia

Cause:
Slowness
Slurring of speech (dysarthria) 
Incoordination
Unsteady gait- cerebellar ataxia- staggering
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10
Q

What is Charcot’s Triad?

A

Nystagmus
Dysarthria
Intention tremor
Tells you who has cerebellar disease

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11
Q

What are the 3 layers of meninges

A

Dura mater- endosteal (closer to skull), meningeal (closer to brain)
Arachnoid layer
Pia mater

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12
Q

Which layer contains CSF?

A

Subarachnoid space

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13
Q

What is the cranial cavity?

A

Space within skull

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14
Q

What in the arachnoid matter, returns CSF into superior sagittal sinus?

A

Villi project as lumps-Arachnoid granulations

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15
Q

Pain from the dura matter is perceived as a headache from which nerve?

A

Trigeminal nerve

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16
Q

Where is CSF located?

A

Later, third, fourth ventricle

17
Q

Where is CSF produced?

A

Choroid Plexus

18
Q

How are 3rd and 4th ventricle connected?

A

Cerebral aqueduct of sylvius

19
Q

How is 2nd and 3rd ventricle connected?

A

Interventricular foramen

20
Q

Which level does spinal cord finish for adults?

A

L1 and L2

21
Q

Which lvl does spinal cord finish for children?

A

L3

22
Q

Conus Medullaris

A

End of spinal cord

23
Q

Cauda Equina

A

Spinal nerves descending below conus medullar is into a bundle

24
Q

Where is the grey matter in the spinal cord?

A

Centre

25
Q

Lateral horn of spinal cord only present at what level?

A

Thoracic and upper lumbar

26
Q

Reason for bilateral brainstem lesion?

A

Stroke, tumour, MS

27
Q

Symptoms of unilateral brainstem lesion?

A

It is an UMN lesion
Contralateral side spastic hemiparesis (weakness of muscles- for body)
Contralateral (for body) Hyperreflexia (increases exaggerated reflexes)
Extensor plantar response
Sensation on opposite side too (for body)

For face it is ipsilateral side due to cranial nerves being LMN

28
Q

Are cranial nerves UMN or LMN?

A

LMN