Structure and function of the human nervous system- Part 2 Flashcards
Frontal lobe
includes all the cortex anterior to the central sulcus. This region is especially large in humans, relative to other animals and is responsible for our unique ability to plan, reason, and reflect on our own behaviours
Parietal lobe
includes cortex located behind the central sulcus, caudal to the frontal lobe and dorsal to the temporal lobe. In the left hemisphere this region plays a special role in aspects of language comprehension and mental arithmetic; in the right it is involved in representing the locations of salient objects in space
Temporal lobe
includes cortex located ventral to the frontal and parietal lobes. In the left hemisphere this region plays a role in understanding the spoken and written word; in the right it may be particularly involved in recognising complex objects and faces
Occipital lobe
includes the cortex at the back of the brain, caudal to the parietal and temporal lobes. Cortex in this are processes various aspects of visual information, such as motion, colour, shape and so on
The corpus callosum
nerve fibres that connect the two hemispheres of the brain
myelinated axons extend from one hemisphere to the other
the corpus callosum contains about 200 million axons
Homotopic fibres
connect corresponding regions of the cortex in the two hemispheres
Heterotopic fibres
connect different cortical regions of the two hemispheres
Ipsilateral fibres
connect adjacent regions within the same hemisphere
Limbic system
The hippocampus and parts of the cortex that surround it are involved in learning and memory rather than emotional behaviour
amygdala- fear conditioning/mediating emotions
hippocampus- formation of long term memories
cingulate gyrus- emotional processing in response to pain
Basal ganglia
a collection of nuclei buried deep within each hemisphere that are classified as grey matter
caudate nucleus- (‘nucleus with a tail’)
putamen- (‘shell’)
globus pallidus- (‘pale globe’)
The nuclei of the basal ganglia are responsible for controlling movement, particular those aspects that are highly automatised or involuntary (such as walking. The basal ganglia are dysfunctional in patients with Parkinson’s disease.
Diencephalon
the second major devision of the forebrain is the diencephalon. It surrounds the third ventricle, in the middle of the brain, and consists of two major parts: the thalamus and hypothalamus
Thalamus
forms the dorsal part of the diencephalon. It is a major relay station for sensory information being conveyed to the cerebral cortex
lateral geniculate nucleus and medial geniculate nucleus (part of the thalamus)
Lateral geniculate nucleus receives information from the retina of the eye and sends axons to the primary visual cortex
Medial geniculate nucleus receives information from the inner ear and sends axons to the primary auditory cortex
Hypothalamus
controls the autonomic nervous system and the endocrine system; it also regulates survival behaviours such as fighting, feeding, fleeing and mating
Mesencephalon (tectum & tegmentum)
located towards the base of the brain, and is anatomically the junction between the cerebrum and spinal cord
tectum (superior and inferior colliculi)
Superior colliculi have a role in both auditory and visual processing, and may also have an important role in spatial organisation
Inferior colliculi play a critical role in auditory processing, and in particular our ability to localise sounds in the environment
tegmentum (reticular formation)
formed from complex networks of axons and dendrites. The reticular formation, which is widely connected with various parts of the brain and spinal cord, plays a vital role in sleep, arousal (the ability to remain conscious and alert), and various reflexes. Damage to this part of the brain stem can cause coma or death.
tegmentum (substantia nigra)
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Metencephalon and Myelencephalon
the two divisions of the hindbrain
Metencephalon (pons)
the pons lie on the ventral surface of the brainstem. It contains several nuclei important for regulating sleep and arousal; it also relays information form the cerebral cortex to the cerebellum, via the cerebellar peduncles
Myelencephalon (medulla)
the medulla links the hindbrain to the spinal cord, and contains neurons important for autonomic functions like respiration and heart rate
Metencephalon (cerebellum)
- has more neurons than the cortex
- important role in motor function/ rapid changes in motor function
- makes adjustments to what muscles are doing
- Damage leads to subtle forms of motor impairment and difficulties with balance
Spinal column
24 individual vertebrae cervical- neck thoracic- chest lumbar- lower back sacral- pelvic region
Spinal foramen
the hollow channel in which the spinal cord resides
What is the purpose of the spinal cord?
to transmit somatosensory information (touch, temperature and pain) from the body to the brain, and to distribute motor axons to the various organs (glands and muscles)
Spinal cord
Grey matter is surrounded by white matter (cell bodies are on the inside)
surrounded by 3 meninges
31 pairs of spinal nerves (to receive and convey information)
dorsal and ventral roots
the dorsal root emerges from the dorsolateral surface of the spinal cord and the ventral root emerges from the ventrolateral surface
The fibres contained within the pair of roots emerging from each side of the spinal cord join together as they exit from gaps in the vertebrae, and form and individual spinal nerve
What purpose do the spinal nerves serve?
the purpose of the spinal nerves is to receive information form the sensory receptors they innervate, and convey information from the brain to the glands and muscles of various parts of the body
Dorsal root ganglia
afferent somatosensory
afferent neuron axons- dorsal roots
afferent cell bodies- dorsal root ganglia
Ventral root ganglia
efferent, motor (muscles and glands)
efferent neuron axons- ventral root
efferent cell bodies- grey matter of spinal cord
cranial nerves
serve the sensory and motor functions of the head and neck
Autonomic nervous system
- regulates smooth muscle, (skin, blood, vessels, eyes, walls and sphincters of internal organs), cardiac muscles and glands
- controls blood pressure, temperature, digestion, sexual functioning
- consists of two antagonistic systems the sympathetic (arousing) and parasympathetic (calming)
- opposite functional consequences
- while one system is active the other one is inactive
- both have distinct neural pathways despite working together
where are the cell bodies of the sympathetic nervous system located?
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where are the cell bodies of the parasympathetic nervous system located?
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