Structure and function of the eye Flashcards

1
Q

Label the bony orbit and the surface anatomy of the eye

A

Kenhub/netters

1) Upper and lower eye lid make up the palpebral fissure.
2) Lateral canthus
3) Pupil
4) Iris
5) Sclera
6) Medial canthus
7) Caruncle
8) Limbus - border of the iris from the sclera
9) Tear film covers the eye - lubricates the eye but also has visual function.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Describe the lacrimal system

A

Lacrimal System
– Tear produced by the Lacrimal Gland
– Tear drains through the two puncta, opening on medial lid margin
– Tear flows through the superior and the
inferior canaliculi
– Tear gathers in the Tear Sac
– Tear exits the Tear Sac through the tear
duct into the nose cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What causes tear production?

A
– Basal Tears
– Reflex Tears – in response to irritation • Afferent – Cornea – CN V1 (Ophthalmic
Branch of Trigeminal Nerve)
• Efferent – Parasympathetic
• Neurotransmitter - Acetylcholine
– Crying (Emotional) Tears
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the function of the tear film?

A
• Tear film maintains smooth
cornea-air surface
• Oxygen Supply to Cornea – Normal cornea has no blood
vessels
• Removal of Debris (Tear film and
Blinking)
• Bactericide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the layers of the tear film?

A

– Superficial Oily (lipid) Layer to reduce tear film evaporation (produced by a row of Meibomian Glands along the lid margins)
– Aqueous Tear Film (Tear Gland)
– Mucinous Layer on the Corneal. Surface to maintain surface wetting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the conjunctiva?

A
  • The conjunctiva is the thin, transparent tissue that
    covers the outer surface of
    the eye.
  • It begins at the outer edge of the cornea, covers the visible part of the eye, and lines the inside of the
    eyelids.
  • It is nourished by tiny blood vessels that are nearly invisible to the naked eye.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Label a cross section of an eye and describe the three layers of the eye?

A

Netters/ken hub

  • Cornea
  • Iris
  • Ciliary body (produces aqueous humour)
  • rectus muscle
  • optic disk
  • optic nerve
  • vitreous humour
  • lens
  • aqueous humour
3 layers of the eye
– Sclera – Hard and
Opaque
– Choroid – Pigmented
and Vascular (so it can provide nutrients for the retina which is very energy demanding)
– Retina – Neurosensory
Tissue
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe the sclera

A
  • The sclera, commonly known as “the white of the
    eye,” is the tough, opaque tissue that serves as the eye’s protective outer
    coat.
  • High water content
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the cornea and its function?

A
  • The cornea is the transparent, dome-shaped window covering the front of the eye. It is a powerful refracting surface, providing 2/3 of the eye’s focusing power. Like the crystal on a watch, it gives us a clear window to look through
  • Low water content
  • It is continuous with the scleral layer
  • Physical and infection barrier
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Describe the structure of the cornea?

A
Structure – 5 Layers
– 1 – Epithelium
– 2 – Bowman’s Membrane
– 3 – Stroma – regularity
contributes towards
transparency
• Corneal nerve endings
provides sensation and
nutrients for healthy tissue
• No blood vessels in normal
cornea
– Descemet’s Membrane
– Endothelium – pumps fluid
out of corneal and prevents
corneal oedema, 
• Only 1 layer of endothelial
cell
• No regeneration power
• Endothelial cell density
decreases with age
• Endothelial cell dysfunction
may result in corneal
oedema and corneal
cloudiness. This is what happens if you hydrate the cornea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe the UVEA

A
Vascular coat of eye ball and lies between the sclera and retina.
Uvea is composed of three parts.
• Iris
• ciliary body
• choroid.
These three portions are
intimately connected and a
disease of one part also affects the other portions though not necessarily to the same degree.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe the choroid

A

The choroid lies between the retina and sclera. It is composed of layers of blood vessels that nourish the back of the eye.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe the Iris

A
  • The coloured part of the eye is called the iris. It controls light levels inside the eye similar to the aperture on a camera. So if the pupil is dilated the focus is on the subject but the foreground and background are blurry.
  • The round opening in the centre of the iris is called the pupil.
  • The iris is embedded with tiny muscles that dilate (widen) and constrict (narrow) the pupil size.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the structure and function of the lens

A

Structure
– Outer Acellular Capsule
– Regular inner elongated cell fibres – transparency
– May loose transparency with age – Cataract

Function:
– Transparency
    • Regular structure
– Refractive Power
    • 1/3 power
    • Higher refractive index than aqueous fluid and vitreous
– Accommodation
    • Elasticity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the lens zonules?

A

Lens is suspended by a
fibrous ring known as lens
zonules, consists of passive
connective tissue. It connects the lens to the ciliary muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the retina?

A
- The retina is a very thin
layer of tissue that lines the
inner part of the eye.
 - It is responsible for
capturing the light rays that
enter the eye. Much like
the film's role in
photography.
 - These light impulses are
then sent to the brain for
processing, via the optic
nerve.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the optic nerve?

A
  • The optic nerve transmits electrical impulses from the
    retina to the brain. Retinal ganglion neurones
  • It connects to the back of the eye near the macula.
  • The visible portion of
    the optic nerve is called the optic disc.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the macula?

A
  • The macula is located roughly in the centre of the retina, temporal to the optic nerve.
  • Macula Lutea (yellow patch), pigmented region at the centre of the retina of about 6 mm in diameter
  • It is a small and highly sensitive part of the retina responsible for detailed central vision.
  • The fovea is the very centre of the macula. The macula allows us to appreciate detail and
    perform tasks that require
    central vision such as reading.
19
Q

What are the anterior and posterior segments of the eye?

A

Anterior Segment – Ocular
structure anterior to the lens. Aqueous humour

Posterior Segment – Ocular
structure posterior to the lens. Vitreous humour

20
Q

What is the anterior chamber?

A

– Between Cornea and Lens
– Filled with Clear Aqueous
Fluid (produced by the ciliary epithelium of the ciliary bodies)
– Supplies nutrients

21
Q

Describe the ciliary bodies?

A

• Ciliary Body: sites medial to the ciliary muscle
– Secretes aqueous fluid in the eye
• Intraocular Aqueous Fluid flows anteriorly into the Anterior Chamber along the
green arrow (see diagram)
• Aqueous Fluid supplies nutrient
• Trabecular Meshwork drains the fluid out of the eye out through the angle.
• Once through it is abosrbed via two pathways. Uveal-scleral 10-20% (passive) outflow and TM canal of schlemm 80-90% (active).
• Normal Intraocular Pressure – 12-21mmHg

22
Q

Describe the Schlemm’s canal?

A

Modified vein that sits around the trabecular meshwork where the aqueous is actively absorbed.

23
Q

Define glaucoma

A

Optic neuropathy with
characteristic structural damage to the optic nerve, associated with progressive retinal ganglion cell death, loss of nerve fibres and visual field loss

Glaucoma
– Medical Condition of Sustained Raised Intraocular Pressure (risk factor - remember high pressure does not always mean glaucoma. It just means a higher risk of developing it)
– Retinal Ganglion Cell Death and Enlarged Optic Disc Cupping
– Visual Field Loss,
Blindness

24
Q

What are the types of glaucoma

A

Primary Open Angle Glaucoma (Left) – Commonest
• Trabecular Meshwork Dysfunction

Closed Angle Glaucoma – can be acute or chronic
• Increased pressure pushing the iris/lens complex forwards, blocking the trabecular meshwork – vicious cycle
• Risk factors - small eye
(hypermetropia), narrow angle at trabecular meshwork
• May present with sudden
painful red eye with acute drop in vision
• Can be treated with peripheral laser iridotomy to create a drainage hole on the iris

See diagram

25
Describe what can be seen through an ophthalmoscope
See diagram
26
Where is blind spot?
Where the optic nerve meets the retina there are no | light sensitive cells. It is a blind spot.
27
Describe the fovea?
- Your fovea is the most sensitive part of the retina. - It has the highest concentration of cones (colour), but a low concentration of rods. - Fovea has the highest concentration of photoreceptors for fine vision - This is why stars out of the corner of your eye are brighter than when you look at it directly. - But only your fovea has the concentration of cones to perceive in detail. - Fovea forms the pit at the centre of the macula due to absence of the overlying ganglion cell layer
28
What is the difference between central and peripheral vision?
Central Vision (Cones) – Detail Day Vision, Colour Vision – Fovea has the highest concentration of cone photoreceptors – Reading, Facial Recognition – Assessed by Visual Acuity Assessment – Loss of Foveal Vision – Poor visual acuity Peripheral Vision (Rods) – Shape, Movement, Night Vision – Navigation Vision – Assessed by Visual Field Assessment – Extensive loss of Visual Field – unable to navigate in environment, patient may need white stick even with perfect visual acuity
29
Describe retinal structure
Outer Layer – Photoreceptors (1st Order Neuron) – Detection of Light Middle Layer – Bipolar Cells (2nd Order Neurons) – Local Signal Processing to improve contrast sensitivity, regulate sensitivity Inner Layer – Retinal Ganglion Cells (3rd Order Neurons) – Transmission of Signal from the Eye to the Brain See slides
30
What are the two main classes of photoreceptors in the retina?
Rod Photoreceptor • More sensitive to light than cones • Responsible for night vision (Scotopic Vision - Peripheral and Night Vision. Recognises motion) Cone Photoreceptor • Less sensitive to light, but faster response • Responsible for day light fine vision and colour vision (Photopic Vision - Central and Day Vision. Recognises colour and details) Photoreceptors have different frequencies
31
Describe the distribution of photoreceptors
The highest concentration of rod photoreceptors lie 20-40 degrees away from fovea See graph
32
How do you test colour blindness test?
Ishihara test - can test for only red-green deficiencies only. The most common form of colour deficiency is red-green confusion. Patients with colour vision deficiencies will not recognise any pattern or recognise the wrong pattern
33
What is light dark adaption?
``` Dark Adaptation – Increase in light sensitivity in dark – Biphasic Process • Cone adaptation 7 minutes • Rod adaptation 30 minutes – regeneration of rhodopsin ``` ``` Light Adaptation – Adaptation from dark to light – Occurs over 5 minutes – Bleaching of photo-pigments – Neuro-adaptation – Inhibition of Rod/Cone function ``` ``` Pupil Adaptation (minor) – Constriction of pupil with light ```
34
What are the two types of lenses?
Convex lens - converging lens, always have focal point after the lens Concave lens - diverging lens, always have focal point before the lens
35
Define emmetropia
Adequate correlation between axial length and refractive power Parallel light rays fall on the retina (no accommodation)
36
Define Ametropia
Mismatch between axial length and refractive power ``` Parallel light rays don’t fall on the retina (no accommodation) – Nearsightedness (Myopia) – Farsightedness (Hyperopia) – Astigmatism – Presbyopia ```
37
Describe myopia
Parallel rays converge at a focal point anterior to the retina Etiology : not clear , genetic factor Causes – excessive long globe (axial myopia) : more common – excessive refractive power (refractive myopia) Treatment - you need a concave lens Symptoms – Blurred distance vision – Squint in an attempt to improve uncorrected visual acuity when gazing into the distance – Headache`
38
Describe hyperopia
Parallel rays converge at a focal point posterior to the retina Etiology : not clear , inherited Causes – excessive short globe (axial hyperopia) : more common – insufficient refractive power (refractive hyperopia) Treatment - You need a convex lens - surgery Symptoms – visual acuity at near tends to blur relatively early • nature of blur is vary from inability to read fine print to near vision is clear but suddenly and intermittently blur • blurred vision is more noticeable if person istired , printing is weak or light inadequate – asthenopic symptoms: eyepain, headache in frontal region, burning sensation in the eyes, blepharoconjunctivitis – Amblyopia – uncorrected hyperopia > 5D
39
Describe Astigmatism
Parallel rays come to focus in 2 focal lines rather than a single focal point Etiology : heredity Cause : refractive media is not spherical-->refract differently along one meridian than along meridian perpendicular to it-- >2 focal points (punctiform object is represent as 2 sharply defined lines) ``` Symptoms – asthenopic symptoms ( headache , eyepain) – blurred vision – distortion of vision – head tilting and turning ``` Treatment – Regular astigmatism :cylinder lenses with or without spherical lenses(convex or concave), Sx – Irregular astigmatism : rigid CL , surgery LOOK UP
40
What is the near response triad?
Adaptation for Near Vision ``` Near Response Triad – Pupillary Miosis (Sphincter Pupillae) to increase depth of field – Convergence (medial recti from both eyes) to align both eyes towards a near object – Accommodation (Circular Ciliary Muscle) to increase the refractive power of lens for near vision ```
41
What is Presbyopia
``` • Naturally occurring loss of accommodation (focus for near objects) • Onset from age 40 years • Distant vision intact • Corrected by reading glasses (convex lenses) to increase refractive power of the eye ``` ``` Treatment – convex lenses in near vision • Reading glasses • Bifocal glasses • Trifocal glasses • Progressive power glasses ```
42
What are the different types of optical correction?
Spectacle lenses – Monofocal lenses : spherical lenses , cylindrical lenses – Multifocal lenses Contact lenses – higher quality of optical image and less influence on the size of retinal image than spectacle lenses – indication : cosmetic , athletic activities , occupational , irregular corneal astigmatism , high anisometropia , corneal disease Contact lenses – disadvantages : careful daily cleaning and disinfection , expense – complication : infectious keratitis , giant papillary conjunctivitis , corneal vascularization , severe chronic conjunctivitis Intraocular lenses – replacement of cataract crystalline lens – give best optical correction for aphakia , avoid significant magnification and distortion caused by spectacle lenses Surgical correction – Keratorefractive surgery :RK, AK, PRK, LASIK, ICR, thermokeratoplasty – Intraocular surgery : clear lens extraction (with or without IOL), phakic IOL
43
Describe the mechanism of accomodation
– Contraction of the Circular Ciliary Muscle inside the Ciliary Body – This relaxes the zonules that are normally stretched between the ciliary body attachment and the lens capsule attachment – Note that zonules are passive elastic bands with no active contractile muscle – In the absence of zonular tension, the lens returns to its natural convex shape due to its innate elasticity – This increases the refractive power of the lens Mediated by the efferent Third Cranial Nerve