Structure and Function Flashcards
What is the Mass-balance equation?
(filtration + secretion) - reabsorption = excretion
What are the functional units of the kidney?
Nephrons
How is blood filtered?
Through the glomerulus
What is the renal corpuscle consist of?
Bowman’s capsule and glomerulus
What produces renin?
Granular cells of the afferent arteriole of the juxtaglomerular apparatus
What is driven by a gradient in hydrostatic pressure, which causes water to be filtered from plasma across the glomerular membrane
Glomerular filtration
What is known as glomerular filtration as it removes water and some solutes from plasma?
ultrafiltration
What pathway is direct from lumen to interstitial space via tight junctions, driven by electrochemical forces
paracellular pathway
What pathway requires a transport mechanism across both the apical and basolateral membranes via some sort of diffusion
transcellular pathway
What type of diffusion is when the solute molecule passes freely across the apical membrane without the need for any channel or “assistance
Simple diffusion
What type of diffusion is when the solute interacts with a specific protein (uniport) in the membrane that facilitates its movement across the membrane
Facilitated diffusion
What type of diffusion is when two different solutes are both transported in the same direction (symport) or opposite directions (antiport) by interaction with a transport protein
Coupled transport diffusion