Structural pathologies and vascular lesions Flashcards
What are the 4 classifications of voice pathologies?
- Structural
- Vascular
- Neurological
- Functional
What are structural pathologies of the vocal folds?
- Change in structure of the mucosa of the VFs
- Knowing what layer the pathology affects can give an idea of sound produced
- Nodules, polyps, cysts, laryngitis, contact ulcers/granuloma, papilloma, sulcus vocalis, carcinoma
What are nodules? (What, who, why, where)
INFLAMMATORY DEGENERATION OF SLLP, FIBROSIS AND OEDEMA
- One of the most common benign VF pathologies
- Results from phonotrauma (excessive use, people with heavy vocal load)
- Can occur at any age
- More common in children and females (shorter VFs, more vibration, less HA in F)
- May be minimally symptomatic
- Typically form bilaterally at anterior/middle 2/3 of VF
- Areas of high vibratory impact and stress
- Vary in size: pinhead to pea
What are the 3 types of nodules?
- Acute
- Due to traumatic/hyperfunctional use
- Appear gelatinous from oedema in Reinke’s space while epithelium remains normal - Chronic
- Appear firm, callous-like
- Fixed to underlying mass of mucosa due to increased fibrosis, thickened epithelium - Reactive nodular change
- People with polyp, cyst, other mass lesions
- Creates contralateral reaction on other VF
What are the perceptual signs of nodules?
- Subtle changes in early stage
- Mechanical effect on VF depends on size
- Roughness
- Breathiness
- Fatigue
- Singers: loss of vocal range
What are the physiological signs of nodules?
- Increased glottal flow
- Increased respiratory effort
- Increased demands on VF due to laryngeal hyperfunction and asymmetric VF vibration
What are the acoustic signs of nodules?
- May present as normal
- Increased frequency and amplitude perturbation (jitter, shimmer), cycle-to-cycle variation in freq and amp, random changes
- Reduced phonation range
- Increased s/z ratio
What are the visual signs of nodules?
- Increased mass/thickness of VF cover
- Hourglass closure pattern or posterior chink
- Incomplete closure around site of nodules
- Reduced mucosal wave at site
Management of nodules
- Behavioural modification
- Voice therapy
- Surgery not typical
What are polyps?
FLUID-FILLED WITH OWN BLOOD SUPPLY
- Caused by phonotrauma, often one incidence of vocal abuse
- Sudden onset and size increase
- Often unilateral, can produce reactive nodule
- Originate in SLLP
- Typically form in middle 1/3
- Can be subglottic but normally on superior region
What are the 3 types of polyps?
- Sessile - blister-like
- Pedunculated - attached to stalk
- Haemorrhagic
What are the perceptual signs of polyps?
- Similar to nodules
- Depends on size and site, interfere with closure
- Roughness
- Breathiness
- Diplophonia
- Globus sensation
What are the physiological signs of polyps?
- Increased airflow
- Increased subglottal pressure
- Decreased closing times of VF
What are the acoustic signs of polyps?
- Similar to nodules
- Perturbations
- May present as normal
- Increased frequency and amplitude perturbation (jitter, shimmer), cycle-to-cycle variation in freq and amp, random changes
- Reduced phonation range
- Increased s/z ratio
What are the visual signs of polyps?
- Appear translucent, can be red
- Asymmetrical closure
- Increased aperiodicity
- Increased mass
Management of polyps
- Behavioural therapy
- Voice therapy
- Vocal hygeine
- Surgery
- 7% see an ENT
What are cysts?
BENIGN MUCOUS FLUID LESION SURROUNDED BY A MEMBRANE
- Caused by phonotrauma or glandular blockage
- Near VF surface
- Predominantly unilateral
- Can co-occur with nodules
- Slight yellow colour due to mucous buildup, doesn’t drain spontaneously
- Can rarely present congenitally
What are the 2 types of cysts?
- Epidermoid: like cysts on skin
- Retention: glandular blockage
What is the difference between polyps and cysts?
Polyp = blister-like bump from traumatic event
Cyst = Fluid-filled sac from repetitive trauma or clogging in VF mucous glands
Cysts often mistaken for polyps
What are the perceptual features of cysts?
- Roughness
- Lowered pitch
- Throat clearing due to globus sensation, depends on size
What are the physiological features of cysts?
- Higher than average airflow
- Slower closing phase
What are the acoustic signs of cysts?
- Lowered f0
What are the visual signs of cysts?
- Hard to identify
- Sometimes highlighted by a persistent light reflection from slightly raised area
- Absence of mucosal wave at site
- Aperiodicity and lack of closure
Management of cysts
- Therapy not usually effective
- Surgery
What is laryngitis?
GENERAL TERMS FOR VARIOUS INFLAMMATORY CONDITIONS
- Caused by medical diagnoses such as exposure to irritants, GORD, environmental agents, upper respiratory tract infection, chronic phonotrauma, can be primary or secondary aetiology
- May lead to tissue changes like nodules
What are the perceptual features of laryngitis?
- Roughness
- Difficulty speaking in a low voice
- Pitch higher or lower
- Difficult to get volume
- Sore throat
What are the physiological features of laryngitis?
- Increased airflow
- Increased pressure
What are the acoustic features of laryngitis?
- Perturbation
- Increased or decreased f0
- Greater than normal spectral noise
What are the visual signs of laryngitis?
- Redness
- Oedema
- May be VF asymmetry and aperiodicity
- Reduced/absent mucosal wave
- Stiff jerky movement
Management of laryngitis
- Rest and hydration
- Antibiotics if indicated
What are contact ulcers/granulomas?
BENIGN GROWTHS ALONG VOCAL PROCESSES
- Bilateral or unilateral
- Contact ulcers = raw sores, little protective tissue
- Granulomas = tend to grow over contact ulcer until cause of irritation is resolved
What are the 3 causes of contact ulcers/granulomas?
- Laryngopharyngeal reflux irritation - irritation causing damage to localised tissue
- Intubation (granuloma) - can spontaneously resolve
- Phonotrauma
What are the perceptual features of contact ulcers/granuloma?
- Globus sensation
- Chronic throat clearing and cough
- Reduced pitch range
- Roughness
- Breathiness
- Difficulty increasing loudness
- Pain during swallowing
What are the visual features of contact ulcers/granuloma?
- Prevent VF closure
- Unilateral phase assymetry
Management of granuloma
- Depends on aetiology
- Reflux: diet, lifestyle, meds, invasive surgical treatment
- Intubation: can resolve spontaneously, steroid injection
- Phonotrauma: voice behavioural therapy
What is candida?
FUNGAL INFECTION
- Consequence of weakened immune system
What are the perceptual features of candida?
- Pain
- Pressed voice
- Hoarseness
- Breathiness
What are the visual features of candida?
- Oedema
- Erythema
- VF edges irregular, stiff
- Incomplete glottic closure
- Decreased mucosal wave
- Asymmetric weakness of VF
Management of candida
- Medication
- Oral hygeine
What is papilloma?
BENIGN TUMOUR CAUSED BY EXPOSURE TO HPV VIRUS
- Childhood or adulthood
- Common sites at true VF, trachea, bronchi, palate, nasopharynx
- Juvenile papillomas occur within first 5yrs, contracted from infected mother
- Papillomas can recur rapidly, surgery every 2-4 weeks to minimise threat to airway
- Substantial impact on vocal quality due to frequent surgeries and scarring
- Recurrence rate slower in adult form
What are the perceptual signs of papilloma?
- Roughness (asymmetric VF vibration)
- Breathiness (if closure affected)
- SOB and inspiratory stridor (if lesions are large and diffuse)
- Chronic cough
- Periods of aphonia
What are the visual features of papilloma?
- Incomplete glottal closure
- ‘Wart/raspberry’ appearance
- Increased stiffness of VFs (lesion/scarring), impeded vibratory amplitude
- Mucosal wave may be absent in lesion area
Management of papilloma
- Ensure airway efficiency
- Voice quality secondary
- Laser surgery
- Microsurgery and drug therapy (with side effects)
- Tracheotomy, photodynamic therapy, antiviral drugs
- Non-useful treatment includes steroids and voice treatment as primary treatment
What is laryngeal web?
WEB OF TISSUE JOINING VFS TOGETHER
- 75% occur at birth
- Can be acquired from intubation, trauma
- Failure of recanalisation of larynx during embryonic dev (4-10th week)
- Can block up to 75% of glottal airway
- Thickness varies
What are the perceptual features of laryngeal web?
- SOB
- Inspiratory stridor
- Roughness
- Difficulty sustaining phonation
Management of laryngeal web
- Resection of web
What is sulcus vocalis?
THINNING OR LOSS OF SLLP TISSUE
- Aetiology unclear
- Possibly poor vocal behaviours, congenital, chronic inflammatory processes
What are the perceptual features of sulcus vocalis?
- Roughness
- Weakness
- Increased effort
- Vocal fatigue
What are the visual signs of sulcus vocalis?
- Groove or furrow on medial surface of VF
- Sulcus area doesn’t vibrate normally during voicing
- Tissue loss causes spindle-shaped glottic gap
Management of sulcus vocalis
- Resection
What is carcinoma?
CANCER IN EPITHELIAL TISSUE
- Can affect structures of oral cavity, pharynx and larynx
- Smoking is a primary aetiology
- Men > women 5:1
Roughness is primary sign
What is carcinoma
CANCER THAT FORMS IN EPITHELIAL TISSUE
- Can affect structures of oral cavity, pharynx, larynx
- Smoking is a primary aetiology
- Men > women 5:1
- Roughness is a primary sign
What are some vascular lesions affecting voice?
- Haemorrhage
- Varix and ecstasy
- Inhalation and thermal trauma
What is haemorrhage?
- Typically unilateral
- Appears red and yellowish
- Significant swelling
- Typically a result of a single traumatic event
- Can be result of heavy voice use and use of anticoagulants and salicylates (eg. aspirin), or extended steroid use
- Results in dysphonia/aphonia
Management of haemorrhage
- Surgery (prevention)
- Complete vocal rest in acute phase
- Augmentative procedures
What is varix and ecstasia?
Varix = Prominent vein that is enlarge and dilated
Ecstasia = Lesioning of blood vessel
Reduced mucosal wave due to stiffness
What are the perceptual features of varix and ecstasia?
- May be absent
- Loss of vocal range, esp high frequencies
- Roughness
Management of varix and ecstasia
- Vocal rest
- AAC
What is inhalation and thermal trauma?
- Often referred to as chemical tracheobronchitis
- Voice quality secondary concern
- Pathophysiology not well understood: peripheral nerve damage, changes to laryngeal mucosa, CNS damage from hypoxia, subsequent surgery
- Role of treatment may be limited