Structural Heart Disease & Case Studies Flashcards
Which two layers of the heart protect the myocardium (muscle layer)?
Myocardium is protected on the outside by means of the EPICARDIUM and on the inside by means of the ENDOCARDIUM
What process is characteristic of:
a) systole?
b) diastole?
a) Contraction
b) Relaxation
What phase of the cardiac cycle is longer: systole or diastole?
Diastole is slightly longer than systole
Diastole ~2/3 of each heartbeat
Systole ~1/3 of each heartbeat
What two volumetric measurements are important for determining the stroke volume or cardiac output of the heart?
ESV and EDV
EDV - ESV = SV(mL)
What is LV end systolic volume (ESV)?
The volume of blood that stays behind in the heart in left ventricle following systole
What is LV end diastolic volume (EDV)?
The volume of blood in left ventricle just before systole
What are the 2 main phases of each heartbeat?
- Diastole
2. Systole
How many distinct phases can diastole be split into?
4
How many distinct phases can systole be split into?
3
How can you calculate the ejection fraction from stroke volume and end diastolic volume?
SV/EDV = EF(%)
What name can be used to refer to the aortic and pulmonary valves?
Semilunar valves
What are the 7 stages of the cardiac cycle?
- Atrial systole
- Isovolumetric contraction
- Rapid ejection
- Reduced ejection
- Isovolumetric relaxation
- Rapid passive filling
- Reduced passive filling
What are structural heart diseases?
SHD covers a number of defects which affect the valves and chambers of the heart and aorta
Some defects are present at birth (congenital) while others form later in life (adult; due to damage caused by infections etc.)
Name 3 examples of a congenital structural heart disease.
Congenital SHDs inc.
- Atrial septal defect (ASD)
- Ventricular septal defect (VSD)
- Coarctation of aorta
- Patent foramen ovale (PFO)
- Patent ductus arteriosus (PDA)
- Tetralogy of Fallot (TOF)
What are the two main types of defects that can cause structural heart diseases that form later on in life (i.e. not congenital)?
- Valvular dysfunctions (stenosis/regurgitation)
- Muscular defects (cardiomyopathies)
Atrial septal defect (ASD) is an example of what type of heart disease?
Congenital structural heart disease
Ventricular septal defect (VSD) is an example of what type of heart disease?
Congenital structural heart disease
Coarctation of aorta is an example of what type of heart disease?
Congenital structural heart disease
Patent foramen ovale (PFO) is an example of what type of heart disease?
Congenital structural heart disease
Patent ductus arteriosus (PDA) is an example of what type of heart disease?
Congenital structural heart disease
Tetralogy of Fallot (TOF) is an example of what type of heart disease?
Congenital structural heart disease
What is ventricular septal defect (VSD)?
Congenital structural heart disease
When wall between 2 ventricles fails to develop normally —-> hole in the septal wall
This can cause mixing of oxygenated (oxygen-rich) blood from LV with deoxygenated (oxygen-poor) from RV
How might ventricular septal defect (VSD) present in a child?
In a child
- Poor weight gain
- Poor feeding, sweating while feeding
- Palpitations
- Shortness of breath
- Fatigue or weakness
- Fast breathing
- Hard breathing
- Pallor
What interventions might be needed to treat ventral septal defect (VSD)?
If the hole is very large, might require open heart surgery or cardiac catheterisation to manually close it