Strontium ranelate

Question 1

MoA

Answer 1

Bone formation stimulant and reduces bone resorption

Question 2

Initiation

Answer 2

Initiated by a specialist for use in severe postmenopausal osteoporosis OR men at high-risk fracture when other therapies are unsuitable.

Question 3

Side effects

Answer 3

Serious CV diseases
Severe allergic reaction (DRESS)

Question 4

CV

Answer 4

MI and VTE
CV risk assessment before + every 6-12 months

Question 5

DRESS

Answer 5

Drugs rash with eosinophilia and systemic symptoms
Starts with a rash, fever, swollen glands and a high WBC count.
Can affects kidneys, liver and lungs = FATAL

Pt counselling = if skin rash occurs, stop and report