Stroke Flashcards

1
Q

Stroke

A

Sudden death of brain cells due to lack of oxygen and nutrients

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2
Q

Types of stroke

A

Ischaemic

Haemorrhagic

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3
Q

Ischaemic

A

Caused by blockage of blood flow to the brain
Thrombotic or embolic (travelled from somewhere)
Small vessel disease, large artery atherosclerosis, cardio-embolism stroke, cryptogenic (unknown)
Followed by TIA (mini stroke) <24hrs, no LT problems

85%

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4
Q

Haemorrhagic stroke

A

Caused by rupture of an artery in or to the brain
Intracerebral, subarachnoid
Symptoms: headache, nausea, vomiting, reduced consciousness, weakness in one part of the body
High mortality

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5
Q

Non-modifiable risk factors

A
Age
Sex - men higher 
Race - African/Caribbean and SE/E Asia higher and more severe 
Family history 
Previous Ischaemic stroke or TIA
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6
Q

Modifiable risk factors

A

Hypertension, Diabetes
Coronary heart disease, Left ventricular hypertrophy, Asymptomatic carotid stenosis
XS alcohol, smoking, obesity
Fibrinogen, sickle cell disease, factor VIII
oxidative stress, lipoprotein
vWF, WBC count, C-reactive protein
Hormone replacement therapy, oral contraceptive

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7
Q

What is AF?

A

Atrial fibrillation - condition I which the atria beat irregularly instead of beating effectively to move blood into the ventricles

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8
Q

How does AF affect the risk for stroke?

A

Allows blood to slow down/poor, increasing the risk of stroke

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9
Q

Types of AF

A

Paroxysmal - episodes come and go, usually stop within 48hrs without treatment
Persistent - episode lasts longer than 7 days
Long-standing persistent - continuous for >1
Permanent - all the time

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10
Q

Treatment of AF

A

Medications to control heart rate and reduce risk or stroke
If no underlying cause:
1. Medicines to reduce risk of stroke
2. Medicines to control AF (beta blockers)
3. Cardio version
4. Catheter ablation
5. Pacemaker

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11
Q

Symptoms of stroke

A
Weakness/paralysis
Numbness, tingling, decreased sensation
Vision changes 
Speech problems, swallowing difficulty
Loss of memory 
Loss of balance/coordination
Personality and mood changes 
Vertigo
Drowsiness, lethargy, unconscious 
Uncontrolled eye movements or eyelid dropping
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12
Q

How to diagnose stroke

A

Physical examination with medical history
Neurological examination
Radiological examination (CT or MRI)
Monitor for signs and ,ymptoms

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13
Q

What to monitor for if right cerebral hemisphere is location?

A

Visual and spatial awareness

Proprioception

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14
Q

What to monitor if left hemisphere is suspected?

A

Language
Analytical thinking
Math skill

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15
Q

What is the outcome of stroke dictated by?

A

Location
Size of brain damage
Presence of other medical conditions
Possibility of stroke recurring

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16
Q

Treatment of Ischaemic stroke

A

Recombinant tissue plasminogen activator - short TW
Mechanical thrombectomy - physical removal of blood clot from larger arteries
Carotid endarterectomy - surgery to remove carotid plaque

17
Q

Treatments for haemorrhagic stroke

A

No medical therapy - treat hypertension

Surgery to stop or prevent bleeding

18
Q

Other options for treatment

A

Hypothermia - intravascular cooling, surface cooling

Cellular treatment options - stem cells, endothelial progenitor cells

19
Q

Prevention for stroke

A

Control high blood pressure - ACE inhibitors and ARBs
Statins
Control diabetes
Quit smoking, maintain healthy weight, manage stress

20
Q

What to do if you think someone is having a stroke?

A

F ace - ask them to smile, does one side droop?
A rms - lift both arms, does one drift downwards?
S peech - repeat simple sentence, slurred?
T elephone - call 999