Stroke: Flashcards

1
Q

What is a TIA?

A

A transient and reversible episode of sudden onset neurological dysfunction caused by ischaemia, without acute infarction.

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2
Q

How long do symptoms usually resolves by?

A

24hrs

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3
Q

Give the two circulations which can be affected in TIAs:

A

Anterior (carotid territory) - hemiparesis, hemi sensory disturbance, dysphasia, amaurosis fugax

Posterior (vertebrobasilar) - affects brainstem: LOC, bilateral motor/sensory dysfunction, binocular vision

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4
Q

What is amaurosis fugax?

A

Common TIA presentation: Painless transient monocular visual loss - curtain coming down vertically into field of vision. Occurs due to temporary reduction in retinal, opthalmic or ciliary blood flow = retinal hypoxia.

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5
Q

Give 2 DD for TIA:

A
  • Stroke
  • Hypoglycaemia
  • Migraine aura
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6
Q

What investigations should be performed for those with suspected TIA?

A
  • ECG - look for AF
  • Echocardiogram or cardiac monitoring
  • Doppler US of carotids - to assess stenosis
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7
Q

What score is used to asses stroke risk following a TIA?

A

ABCD2 score

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8
Q

What management should ‘high risk’ TIAs have?

A

Refer to specialist assessment within 24hrs of symptom onset.

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9
Q

What management should those with ‘low risk’ TIA have?

A
  • Control CVS risk factors
  • 2 weeks of 300mg aspirin
  • Antiplatelet therapy - clopidogrel 75mg (or modified-release dipyridamole)
  • Statin
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10
Q

What should someone with an TIA not do for 4 weeks?

A

Drive

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11
Q

What is a Cerebrovascular accident defined as?

A

A clinical syndrome caused by disruption of blood supply to the brain, characterised by rapidly developing signs of focal or global disturbance or cerebral functions, lasting more than 24hrs or leading to death.

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12
Q

What is the cause of strokes?

A

Ischaemic (70%)

Haemorrhage (30%)

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13
Q

Give 4 causes of strokes:

A
  • Cardiac emboli
  • Atherthromboemboli
  • CNS bleed (trauma, aneurysm rupture)
  • Hyperviscosity
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14
Q

Give the signs and symptoms based on the area of the stroke:

A

Total anterior circulation stroke (TACS):

  • Unilateral weakness of face, arm and leg
  • Homonymous hemianopia
  • higher cerebral dysfunction (dysphasia)

Partial Anterior Circulation Stroke (PACS):
- 2 of the 3 for a TACS

Posterior Circulation Syndrome (POCS). One of:

  • Cerebellar or brainstem syndromes
  • Loss of consciousness
  • Isolated homonymous hemianopia

Lacunar syndrome (LACS). Subcortical (midbrain, internal capsule) - one of:

  • unilateral weakness of face and arm. arm and leg or all three
  • Pure sensory loss
  • Ataxic hemiparesis
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15
Q

What investigations should be performed in someone with suspected stroke?

A
  • Urgent CT head before treatment (rule out haemorrhagic stroke)
  • MRI
  • BP/ECG/BMs
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16
Q

What is the management of ischaemic stroke?

A
  • Admit to stroke unit (hydration, O2)
  • Thrombolysis - IV Tissue plasminogen activator e.g. anteplase
  • Antiplatelet - 75mg clopidogrel, started 24hr after thrombolysis
17
Q

In what time period must thrombolysis be given in in an ischaemic stroke?

A

4.5 hours of onset.

alteplase

18
Q

What should be done if thrombolysis isn’t appropriate?

A

(e.g. if time of onset is unknown)

  • Aspirin 300mg once daily for 2 weeks
  • Life long clopidogrel (75mg)
19
Q

Who is usually involved in the care of someone who has had a stoke?

A
  • Neurosurgeon
  • Neurologist
  • SALT
  • Physiotherapist
  • Occupational therapist