Stroke

Question 1

what is stroke?

Answer 1

a blocked or burst blood vessel that stops blood flow to parts of the brain

Question 2

what are the two types of stroke

Answer 2

1. Ischemic
   - clot
   a. thrombotic
   b. embolic
2. Hemorrhagic
   - burst vessels
   - can lead to aneuryms

Question 3

what is an aneursm

Answer 3

localized, abnormal weak spot of he blood vesel that causes a bulge

Question 4

what is infarction?

Answer 4

result of prolonged ischmeia

Question 5

what is TTC

Answer 5

tetrazolium chloride staining

• redox indicator for cellular respiration
• white compound is enzymatically reduced to red in living cells by dehydrogenase
• areas of necrosis remain white

Question 6

what is the process of forming a clot?

Answer 6

1. Damaged blood vessel
   - the damaged vessel triggers clotting factors to come to the area
2. Platelet plug
   - vasoconstriction decreases the amount of blood flow to the area
   - platelets form a sticky plug
3. Clot
   - fibrin adheres to the platelets and the RBC to form an insoluble clot

Question 7

what is dangerous about an acute brain ischemia? (3)

Answer 7

can lead to

1. overproduction of free radicals
2. calcium overprodution
3. excitotoxicity that triggers apoptosis

Question 8

what is BE FAST

Answer 8

Balance
Eyes
Face
Arm
Speech
Time

Question 9

what are possible treatments? (4)

Answer 9

1. thmrobolytics
2. drugs that inhibit sodium channel to decrease number of AP
3. drugs that block glutamate receptors
4. drugs that block calcium