Stroke Flashcards
Difference in stroke between Indigenous and non-Indigenous populations
Indigenous Australians have a 1.7x higher stroke rate, 2x higher hospitalisation, 1.6x higher death rate
Types of stroke and their percentage
Ischemic: 87%
Haemorrhagic: 13%
Risk factors for both types of stroke
High BP
Smoking
Diabetes
Physical inactivity
Obesity
High cholesterol
Atrial Fibrillation
Excessive alcohol consumption
Age
Risk factors for ischemic stroke
Atherosclerosis
Atrial fibrillation
Prior ischemic strokes
Risk factors for haemorrhagic stroke
Bleeding disorders
Vascular malformations
Use of anticoagulants
Signs and symptoms of a stroke
FAST
Face droop
Can’t use Arms
Slurred speech
Time
Numbness, strong headache, vertigo and loss of balance, violation of speech, understanding and sight
Predictors of survival at 3 and 12 months post stroke
Age
Verbal component of the Glasgow Coma Scale
Arm power
Ability to walk
Pre-stroke dependency
There’s a 98% chance of walking after stroke if a patient can…
independently sit for 30 seconds and visibly contract muscles in the legs (with or without movement) within 72 hours
There’s a 98% chance of regaining upper limb function after stroke if a patient can…
exhibit some finger extension, some shoulder abduction within 72 hours
Medical treatment of stroke
Thrombolysis: Recombinant tpA
Aspirin
Endovascular thrombectomy
Decompressive surgery (Craniectomy)
Medical prevention of stroke
antithrombotic agents
antiplatelet agents
slow clotting
anticoagulant agents
prevent clotting
advice about risk factors - lifestyle modification
Patient presents <4.5hrs from symptom onset of stroke
tpA - Thrombolysis
Patient presents 6-24hrs from symptom onset of stroke
Endovascular thrombectomy
Why don’t you use tpA after 4.5hrs
tpA thins blood so don’t want to use it after 4.5hrs as there is a high risk of doing further damage
Risk of using tpA
risk of symptomatic Intracerebral Hemorrhage (ICH)
larger more proximal clots are more resistant to tpA
What is thrombectomy
mechanical retrieval of a clot
when is thrombectomy indicated
used for proximal large artery occlusions
Non-medical management of stroke
Doctors
Nurses
Physio’s
OT’s
Speech therapists
Social workers
Psychologists
Dieticians
What is neuropasticity
lifelong capacity of the brain to learn new ways of doing things based on new experiences and learning
What is adaptive plasticity
increased function/neural ability to perform a task
neurophysiological changes that improve the ability to perform tasks
What is maladaptive plasticity
decreased function, impaired ability to perform tasks
plasticity that is unhelpful
examples of unhelpful/maladaptive plasticity
chronic pain, allodynia
8 factors that influence neuroplasticity
use dependent and specific
repetition and intensity: reps required for lasting neural change, greater intensity induces neuroplasticity
time sensitive
task importance, motivation, feedback and attention: more neuroplasticity when training relevant + important tasks, feedback increases quality, attention and focus increase capacity to learn
environment: sensory, cognitive, motor and social stimulation facilitate increased neuroplasticity
adjuvant or adjunct therapies: priming (motor imagery, mental practice, stimulation based therapy) increases neuroplasticity
patient characteristics: younger people more neuroplasticity, stress impairs neuroplasticity
pharmacology: GABA receptor agonists used for anxiety, seizures, spasticity reduce neuroplasticity
Differentiate between use dependent and learning dependent plasticity
Use dependent: use it or lose it. Reorganisation of cortical regions as a result of motor practice
Learning dependent: reorganisation of cortical regions as a result of skill acquisition. Involves task specific training, goal setting, active problem solving, new skills