Stroke Flashcards

1
Q

what is a cerebrovascular accident (CVA) (stroke)?

A

Neurological signs and symptoms, usually focal and acute, that result from disease involving cerebral blood vessels

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2
Q

what is an ischaemic stroke?

A

when the blood supply to an area of brain tissue is reduced, resulting in tissue hypoperfusion

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3
Q

what causes an ischaemic stroke?

A

embolism
systemic hyoperfusion
cerebral vinous sinus thrombosis

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4
Q

pathophys of embolism causing ischaemic stroke?

A

an embolus originating somewhere else in the body (e.g. the heart) causes obstruction of a cerebral vessel, resulting in hypoperfusion to the area of the brain the vessel supplies.

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5
Q

pathophys of thrombosis causing ischaemic stroke?

A

a blood clot forms locally within a cerebral vessel (e.g. due to atherosclerotic plaque rupture).

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6
Q

pathophys of systemic hypoperfusion causing ischaemic stroke?

A

blood supply to the entire brain is reduced secondary to systemic hypotension (e.g. cardiac arrest).

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7
Q

pathophys of cerebral venous sinus thrombosis causing ischaemic stroke?

A

blood clots form in the veins that drain the brain, resulting in venous congestion and tissue hypoxia.

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8
Q

what is a haemorrhagic stroke?

A

secondary to rupture of a blood vessel or abnormal vascular structure within the brain

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9
Q

what are the sub-types of a haemorrhagic stroke?

A

Intracerebral haemorrhage

Subarachnoid haemorrhage

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10
Q

what is an intracerebral haemorrhage?

A

bleeding within the brain secondary to a ruptured blood vessel.

Can be intraparenchymal (within the brain tissue) and/or intraventricular (within the ventricles).

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11
Q

what is a subarachnoid haemorrhage?

A

A type of stroke caused by bleeding outside of the brain tissue, between the pia mater and arachnoid mater.

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12
Q

what are the risk factors for a stroke?

A

hypertension
diabetes mellitus
heart disease (AF, CCF)
heredity
blood lipids, cholesterol, smoking

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13
Q

the anterior cerebral arteries supply…

A

the anteromedial area of the cerebrum

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14
Q

the posterior cerebral arteries supply…

A

a mixture of the medial and lateral areas of the posterior cerebrum

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15
Q

the middle cerebral arteries supply…

A

the majority of the lateral cerebrum

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16
Q

what is a total anterior circulation stroke (TACS)?

A

large cortical stroke affecting the areas of the brain supplied by both the middle and anterior cerebral arteries

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17
Q

how do you diagnose a TACS?

A

all of the following 3 present:
1. unilateral weakness (and/or sensory deficit) of the face, arm and leg
2. homonymous hemianopia
3. higher cerebral dysfunction (dysphasia, visuospatial disorder)

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18
Q

what is a partial anterior circulation stroke (PACS)?

A

less severe than TACS
- part of the anterior circulation has been compromised

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19
Q

how do you diagnose a PACS?

A

2 of the following:
1. unilateral weakness (and/or sensory deficit) of the face, arm and leg
2. homonymous hemianopia
3. higher cerebral dysfunction (dysphasia, visuospatial disorder)

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20
Q

what is posterior circulation syndrome (POCS)?

A

damage to the area of the brain supplied by the posterior circulation (eg. cerebellum and brainstem) and (occipital lobe, thalamus, medial temporal lobe)

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21
Q

how do you diagnose a POCS?

A

1 of the following is present:
1. cranial nerve palsy and a contralateral motor/sensory deficit
2. bilateral motor/sensory deficit
3. conjugate eye movement disorder (eg. horizontal gaze palsy)
4. cerebella dysfunction (eg. vertigo, nystagmus, ataxia)
5. isolated homonymous hemianopia

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22
Q

what is a lacunar stroke (LACS)?

A

subcortical stroke that occurs secondary to small vessel disease. No loss of higher cerebral functions.

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23
Q

how do you diagnose a LACS?

A

1 of the following needs to be present:
1. pure sensory stroke
2. pure motor stroke
3. sensori-motor stroke
4. ataxic hemiparesis
5. clumsy hand-dysarthria

24
Q

what is a transient ischemic attack (TIA)?

A

blood supply to the brain is temporarily blocked

signs are the same as for a stroke but for a shorter duration of time

25
what is important to note with a TIA?
can be a warning that you may have a stroke and an opportunity to prevent this from happening
26
what is a middle cerebral artery (MCA) stroke?
ischemic stroke that occurs in the MCA - can involve the frontal, temporal and parietal lobes
27
what are the features of a MCA?
deficits in movement and sensation of the legs, arms & lower 2/3 of the face difficulty swallowing (dysphagia) impaired speech ability with left MCA impaired vision and partial contralateral blindness headaches hemineglect (right MCA) UL more affected than LL impulsiveness
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symptoms of a MCA in the left hemisphere
* Right hemiparesis - Variable involvement of face and upper and lower extremity * Right-sided sensory loss in a pattern similar to that of the motor deficit - Usually involves all modalities, decreased stereognosis, and agraphesthesia, left-right confusion * Right homonymous hemianopia * Dysarthria * Aphasia, fluent and nonfluent * Alexia, Agraphia, Acalculia, Apraxia
29
symptoms of a MCA in the right hemisphere
* Left hemiparesis - Same pattern as on right * Left-sided sensory loss - Similar pattern that of the motor deficit * Left homonymous hemianopia - Same pattern as on right * Dysarthria * Neglect of the left side of environment * Anosognosia * Asomatognosia * Loss of prosody of speech * Flat affect
30
what is a posterior cerebral artery (PCA) storke?
involvement of the occipital lobe, the medial lobe, the medial temporal lobe or the thalamus
31
what symptoms does a PCA stroke of the occipital lobe cause?
contralateral homonymous hemianopia cortical blindeness (bilateral lesions)
32
what symptoms does a PCA stroke of the medial temporal lobe cause?
*Deficits in long-term and short-term memory *Behaviour alteration (agitation, anger, paranoia)
33
what symptoms does a PCA stroke of the thalamus infarct cause?
–Contralateral sensory loss –Aphasia (if dominant side involvement) –Executive dysfunction –Decreased level of consciousness –Memory impairment
34
what are the clinical features of a brainstem stroke?
–Crossed sensory findings (e.g. ipsilateral face and contralateral body numbness) –Crossed motor findings (ipsilateral face, contralateral body) –Gaze-evoked nystagmus –Ataxia and vertigo, limb dysmetria –Diplopia and eye movement abnormalities –Dysarthria, dysphagia –Tongue deviation –Deafness (very rare) –Locked-in syndrome (can’t move any limb, can’t speak, can sometimes blink)
35
what are the clinical features of a midbrain stroke?
* Ipsilateral 3rd nerve palsy * Contralateral hemiparesis of the arm and leg, sometimes with hemiplegia of the face * Contralateral hemiataxia
36
clinical features of pontine stroke:
*Ipsilateral signs: *Horner’s syndrome *6th or 7th nerve palsy (diplopia, whole side of face is weak) *Hearing loss (rare) *Loss of pain and temperature sense *Contralateral signs: *Weakness in leg and arm *Loss of sensation in arm and leg *Nystagmus, nausea
37
clinical features of a medullary stroke:
*Ipsilateral signs: *Tongue weakness *Sensory loss in face *Horner’s syndrome *Ataxia *Palate weakness (dysphagia) *Contralateral signs: *Weakness, sensory loss in arm and leg *Nausea, nystagmus, dysphagia, dysarthria
38
clinical features of a cerebellar stroke:
*Ischemia involving: *Superior cerebellar artery (SCA) *Anterior or posterior inferior cerebellar artery (AICA or PICA) *Ataxia, vertigo, nausea, vomiting, dysarthria *Often headache and nystagmus *Can also have rapid deterioration in level of consciousness
39
clinical features of a cerebellar infarction
*Infarction causes edema resulting in mass effect, herniation and compression of the fourth ventricle *This can lead to rapid deterioration in level of consciousness *Surgical decompression is often necessary in these circumstances
40
manifestation of cerebellum infarct
DANISH Dysdiadochokinesia: the lack of ability to perform rapidly alternating movements. Ask the patient to quickly supinate and pronate both forearms simultaneously. Movements will be slow and incomplete on the side of the cerebellar lesion. Ataxia: voluntary movement disturbance involves tremor with fine movements eg writing or buttoning the clothes. UL: Finger to nose test- testing tip of the nose with the index finger test the movements are not properly coordinated. LL: ask patient to place the heel of one foot against the shin of the opposite leg. Nystagmus: Ataxia of ocular muscles, a rhythmical oscillation of the eyes. To provoke nystagmus, the patient should rotate eyes horizontally Intention tremor Dysarthria/Scanning speech: ataxia of the larynx muscles, speech is slurred and syllables are separated from one another. Hypotonia: the muscles lose resistance to palpation. The patient walks with a broad-based gait and leans toward the affected side. Rebound phenomenon- Rebound phenomenon is a reflex that occurs when a patient attempts to move a limb against resistance that has been suddenly removed Pendular knee jerk- the leg continues to move several times after the initial reflex
41
what is a lacunar stroke?
occlusion of the penetrating branches of the circle of Wills, middle cerebral stem, and vertebral and basilar arteries, affecting the deep grey and white matter of the cerebrum and brainstem
42
difference between pure motor and pure sensory stroke
Pure motor stroke usually arises from infarction in the posterior limb of the internal capsule; course is often stuttering over hours to days. Pure sensory stroke usually arises from thalamic infarction
43
symptoms of a lacunar stroke:
weakness and sensory loss with no visual field deficit, aphasia, neglect, ataxic hemiparesis (often arises in the corona radiata), clumsy hand-dysarthria (caused by infarction in the pons)
44
signs and symptoms of intracerebral haemorrhage
 Deep location: usually due to rupture of small, deep perforating artery; often associated with hypertension.  Superficial/lobar location: cerebral amyloid angiopathy often the cause; older patients.  Other common causes: arteriovenous malformation/cavernoma; ruptured saccular aneurysm; coagulopathy
45
signs and symptoms of subarachnoid haemorrhage:
thunderclap headache eg “worst headache of my life.” A headache often is associated with nausea, vomiting, and diplopia. Often signs of meningismus, neck stiffness Cranial nerve deficits Often in a state of coma and unconscious
46
what is lock in syndrome?
Basilar artery thrombosis and bilateral infarction of the ventral pons
47
what are the clinical features of lock in syndrome?
Sudden onset Patients develop acute hemiparesis rapidly progressing to quadriplegia and lower bulbar paralysis. Initially the patient is dysarthric and dysphonic but rapidly progresses to mutism (anarthria). Consciousness and sensation is preserved. The patient cannot move or speak but remains alert and oriented. Mortality rates are high (59%), and survivors are left with severe impairments associated with brainstem injury
48
clinical features of wernicke's aphasia
deficit in comprehension and severe difficulty in reading and writing. Lesions causing this problem are usually in the dominant temporal lobe.
49
clinical features of broca's aphasia
comprehension is usually preserved but language expression is affected. Lesions are usually in the dominant frontal lobe. Broca’s aphasia, also called ‘expressive’ or ‘non-fluent aphasia’, may result in almost complete loss of language expression to a slowed, deliberate speech utilizing only key words and simple grammatical structure.
50
what is receptive aphasia?
the problem of understanding language, fluent
51
what is expressive aphasia
the problem of producing the correct word or sequence of words, non-fluent.
52
what causes aphasia?
damage to the regions of the left cerebral cortex
53
what is dysphagia?
difficulty swallowing can lead to aspiration of saliva, food or liquids
54
what is silent aspiration?
when you accidentally inhale food, liquid or other material into your trachea (windpipe or airway) and you don't know it.
55
what is pusher syndrome?
patients actively push away from the nonhemiparetic side, leading to a loss of postural balance The perception of body posture in relation to gravity is altered. The patients experience their body as oriented “upright” when the body actually is tilted to the side of the brain lesion (to the ipsilesional side).
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