Stroke Flashcards
Transient global amnesia
- Onset
- Presentation
Transient global amnesia
- Onset
1. Acute confusion
- Presentation
1. Acute confusion
2. Same question repeatedly
- Neurologically normal
- Able to carry out ADLs
- Procedural memory - No recollection
Stroke mimic
- Migraine similar features
Stroke mimic
- Migraine features
- Blurring of vision
- Pins and needles/numbness
- Difficulty concentrating
Capsular warning syndrome
- Classification
- Features
Capsular warning syndrome
- Classification
1. TIA affecting capsule - Features
1. >3 Episodes of sensory/motor Symptoms
2. High incidence of infarction within 7 days
TOAST Classification
- Classes and Ix
TOAST Classification
- Classes
- Large artery atherosclerosis
- Duplex - Cardio embolic
- ECG/TOE - Small-vessel disease
NIH SS
- Score
NIH Stroke Scale
- Score
- Consciousness& gaze
- Visual and facial palsy
- Motor arm, motor leg, limb ataxia
- Sensory, language and dysarthria
- Extinction/inattention
OCSP
- Classes
Oxford community stroke project
- Classes
TACS
PACS
POCS
LACS
Thrombolysis
- contraindications
Thrombolysis contraindications
- BP>185/110 After two attempts to reduce
- Surgery/trauma/childbirth within 14 days
- Stroke within 14 days
- Active internal bleeding
- Haem abnormalities
- INR 1.7, APTT 40
- DOAC. LMWH
- Platelet<50
- Arterial puncture
- SAH, IE, Pericarditis, pancreatitis, liver disease
Thrombolysis
- Relative contraindications
Thrombolysis
- Relative contraindications
- Infarction >4.5 hr
- Mass effect/oedema/tumor, aneurysm
- Intra cranial/spine surgery
- 2 months - Neurosurgery
- 6 weeks - Stroke/head injury
- 6 weeks - GI/UT bleed
- 6 weeks - Glucose<2.7
- Seizure at stroke onset
- Symptoms start during sleep
Stroke imaging
- 4Ps
Stroke imaging
- 4Ps
- Pipes
-Angiography - Parenchyma
- Non contrast CT - Perfusion
- CT/MRI perfusion scan - Penumbra
- Around ischaemic core
ASPECTS
Scoring
ASPECTS
Scoring
Alberta Stroke Program Early CT Scoring
- Mortality predictor
- Stroke topography
- Stroke size
Alteplase indications
Alteplase indications
- <4.5 hours
- Disabling impairments
- NIH>4
- Dysphagia
- Inability to mobilise/self care
- Visual field defect - No contraindications
Thrombolysis
- Monitoring
Thrombolysis
- Monitoring
- Haemodynamic obs
- Neuro obs
- ICH
- Anaphylaxis
Thrombolysis
- complications
Thrombolysis
- complications
- Reaction
- Rising ICP
Oedema
- Hydrocephalus - Seizure
- Infection
- Metabolic disturbances
- Extra cerebral haemorrhage
- thin pulse, BP, Malaena, abdomen - Intra cerebral haemorrhage
- neuro decline, headache, BP, N&V
Mechanical thrombectomy
- Indications
Mechanical thrombectomy
- Indications
- Large artery occlusion
- MRS>1
- NIHSS - 5 - Fibrinolysis contraindicated
- No response to alteplase
Stroke prevention
- Targets
Stroke prevention
- Targets
- Life style
- Anti thrombotic
- BP
- Lipids
- Glycaemic
- Carotid endarterectomy