Stridor and Sleep Apnoea Flashcards
What structures of the upper airway normally sit above the trachea?
- larynx
- subglottis
How is stridor defined?
- inspiratory wheeze
- due to large airway obstruction
=> (larynx/trachea/major bronchi)
What are the most common causes of stridor in children?
Infections
Foreign Body
Anaphylaxis / angioneurotic oedema
Other (eg burns)
What infections can cause stridor in children?
- Croup (or Pseudomembranous croup)
- Epiglottitis
- Retropharyngeal abscess
- Diphtheria
- Infectious mononucleosis
What can cause stridor in adults?
- Cancers
- Anaphylaxis
- Goitre (retrosternal)
- Foreign body
- Trauma (eg strangulation, burns, irritant gases)
- Other (eg vocal cord palsy; Wegener’s granulomatosis)
What cancers may cause stridor in adults?
- Larynx
- Trachea
- Major bronchi
What is tracheomalacia and when may this cause stridor?
- flaccidity of supporting tracheal cartilage
=> widening of the posterior membranous wall
=> reduced trachea diameter
This causes tracheal collapse
- especially during times of increased airflow
=> coughing, crying, or feeding
How is stridor investigated?
- Laryngoscopy (beware in acute epiglottitis)
- Bronchoscopy
- Flow volume loop
- CXR
- Other imaging (CT; thyroid scan)
How is laryngeal obstruction treated?
- Treat underlying cause
=> eg foreign body removal (Heimlich Manoeuvre) anaphylaxis (adrenaline) - Mask bag ventilation with high flow O2
- Cricothyroidotomy
- Tracheostomy
How is malignant airway obstruction treated?
- Tumour removal
=> laser; photodynamic therapy; cryotherapy; diathermy; surgical resection - Tumour compression
=> intraluminal stent - Radiotherapy
=> external beam; brachytherapy - Chemotherapy
What symptoms would indicate a patient is in acute anaphylaxis?
- Flushing, pruritus, urticaria,
- Angioneurotic oedema (lips, tongue, face, larynx, bronchi)
- Hypotension (vasodilatation and plasma exudation) circulatory collapse (shock)
- Stridor, wheeze and respiratory failure
WHat can potentially cause anaphylaxis in patients?
Foods eg nuts; shellfish
Insect venom (bee, wasp)
Drugs (eg penicillin, aspirin, anaesthetics)
Other eg latex
How is anaphylaxis treated?
IM Adrenaline IV antihistamine IV corticosteroid High flow O2 Nebulised bronchodilators Endotracheal intubation if necessary
How is anaphylaxis prevented?
Allergen avoidance (where possible)
Desensitisation (immunotherapy) eg venom
Self-administered epinephrine
What is meant by obstructive sleep apnoea?
- Intermittent upper airway collapse in sleep
- causes patient to stop breathing for short period (apnoea)
- patient often wakes up => fragmented sleep