Stress and Homeostasis Flashcards

1
Q

What is homeostasis?

A

balanced. maintain stable internal conditions necessary for survival. (goldie locks)

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2
Q

What are stressors in the context of homeostasis?

A

External or internal conditions that challenge homeostasis, requiring the body to adapt.

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3
Q

What is the body’s response to stress

A

Adaptation, which helps restore homeostasis. Failure to adapt leads to illness or death.

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4
Q

What is a negative feedback loop in homeostasis?

A

opposes a change to return the body to a set point (e.g., thermoregulation, blood sugar regulation). Brake petal STOP

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5
Q

Give an example of a positive feedback loop

A

Childbirth: Baby’s head presses on cervix, signals brain to release oxytocin, increases contractions, more pressure on cervix, leading to further contractions.

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6
Q

What is the central stress response?

A

Brain-based response involving arousal, alertness, and inhibition of non-essential functions (e.g., reproduction, growth).

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7
Q

What is the peripheral stress response?

A

Increased respiration, cardiovascular tone, and nutrient distribution to the brain, heart, and skeletal muscles.

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8
Q

What are the three phases of the stress response?

A
  1. Alarm 2. Resistance 3. Exhaustion
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9
Q

What happens during the alarm phase of stress?

A

The body detects the stressor and initiates the “fight or flight” response through the hypothalamus.

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10
Q

What is the role of the hypothalamus in stress?

A

The hypothalamus acts as the control center, triggering the stress response by communicating with effectors.

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11
Q

What is the HPA axis?

A

Hypothalamus-Pituitary-Adrenal axis: A system that regulates stress through cortisol production, promoting adaptation to chronic stress.

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12
Q

What is the role of cortisol in stress?

A

A glucocorticoid hormone that increases blood glucose, regulates Na+/K+ balance, and suppresses immune responses during stress.

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13
Q

What is the sympatho-adrenal medullary (SAS) system?

A

A stress response system mediated by the sympathetic nervous system, secreting catecholamines (epinephrine and norepinephrine) for “fight or flight.”

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14
Q

What are catecholamines and their role in stress?

A

Hormones like epinephrine and norepinephrine that increase heart rate, blood pressure, and prepare the body for acute stress.

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15
Q

What happens during the exhaustion phase of stress?

A

body’s compensatory mechanisms fail, leading to potential illness, disability, or death if homeostasis is not restored.

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16
Q

What is compensatory reserve in stress?

A

The body’s ability to maintain homeostasis before its compensatory mechanisms are overwhelmed.

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17
Q

What factors affect compensatory reserve?

A

Age, health status, duration and intensity of the stressor

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18
Q

How can clinical management increase compensatory reserve?

A

By addressing the underlying problem (e.g., stopping blood loss, providing IV fluids, administering vasopressors).

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19
Q

What is the function of the autonomic nervous system in stress?

A

It controls involuntary responses, with the sympathetic division activating the “fight or flight” response and the parasympathetic division promoting rest.

20
Q

What is physiological stress?

A

Any external or internal condition that challenges the homeostasis of a cell or organism.

21
Q

What is adaptation in response to stress?

A

body adjusts to restore homeostasis after a stressor.

22
Q

What are the central functions during a stress response?

A

Arousal, alertness, cognition, and inhibition of non-essential functions like reproduction and growth.

23
Q

What are the peripheral functions during a stress response?

A

Increased respiration, cardiovascular tone, and nutrient delivery to vital organs (brain, heart, skeletal muscles).

24
Q

What are peripheral chemoreceptors?

A

Receptors that detect changes in blood pH and help regulate breathing and oxygenation.

25
Q

What is the role of the control center in homeostasis?

A

It processes information from receptors, compares it to the set point, and stimulates a response to maintain balance.

26
Q

What is the role of the hypothalamus in homeostasis?

A

It regulates body functions such as temperature, blood pressure, and circadian rhythms through homeostatic mechanisms.

27
Q

What is an effector in homeostasis

A

An organ or tissue that acts to restore homeostasis in response to signals from the control center.

28
Q

What is the role of the renal tubules in homeostasis?

A

They reabsorb water and adjust blood osmolality as part of the homeostatic response to dehydration or fluid imbalance.

29
Q

What is a stressor in the context of homeostasis?

A

Any physical, chemical, or environmental factor that causes a deviation from the body’s normal state.

30
Q

What is the role of receptors in homeostasis?

A

They detect changes in the environment and forward the information to the control center for processing.

30
Q

What is the role of a negative feedback loop in homeostasis?

A

It reduces or opposes a change to bring the body back to its set point, maintaining balance.

31
Q

What is the positive feedback loop in homeostasis?

A

It amplifies or enhances a change, pushing the body further from the set point, often seen in processes like childbirth and blood clotting.

32
Q

What is thermoregulation?

A

The process by which the body maintains a stable internal temperature, usually through negative feedback mechanisms.

33
Q

How does the body regulate blood glucose?

A

Insulin lowers blood glucose when high; glucagon raises it when low, both through negative feedback loops.

34
Q

What is the role of epinephrine in the stress response?

A

It increases heart rate, blood pressure, and energy availability for the “fight or flight” response.

35
Q

What is the role of norepinephrine in the stress response?

A

It helps maintain blood pressure and enhances the contractility of cardiac muscles during stress.

36
Q

What is the autonomic nervous system’s role in stress adaptation?

A

It regulates involuntary functions, with the sympathetic division activating during stress and the parasympathetic calming the body after.

37
Q

What happens when compensatory mechanisms fail during stress?

A

The body can no longer maintain homeostasis, leading to illness, disability, or death.

38
Q

How does the body compensate during hemorrhage?

A

increases heart rate, constricts blood vessels, and redirects blood flow to vital organs to maintain tissue oxygenation.

39
Q

What are glucocorticoids, and how do they function in stress?

A

Hormones like cortisol that help the body respond to stress by increasing blood glucose and suppressing inflammation.

39
Q

What are vasopressors, and how do they help in stress management?

A

Medications that constrict blood vessels, raising blood pressure to improve blood flow to vital organs during stress or injury.

40
Q

What role does cortisol play in the stress response?

A

Cortisol increases blood glucose, regulates immune response, and helps the body manage prolonged stress.

41
Q

What is the “fight or flight” response?

A

physiological reaction triggered by the sympathetic nervous system that prepares the body to face or escape danger.

42
Q

What is the sympathetic nervous system?

A

division of the autonomic nervous system that activates the body’s “fight or flight” response during stress.

42
Q

What is the parasympathetic nervous system?

A

division of the autonomic nervous system that promotes “rest and digest” functions after the stressor has passed.