STREPTOCOCCUS & ENTEROCOCCUS Flashcards
Streptococcus FAMILY
Streptococcacea
Majority of strepto are __ anaerobes
facultative
ANTIGEN Group A
rhamnose-N-acetylglucosamine
ANTIGEN Group B
rhamnose-glucosamine polysaccharide
ANTIGEN Group C
rhamnose-N-acetylgalactosamine
ANTIGEN Group D
glycerol teichoic acid containing D-alanine and glucose
ANTIGEN Group F
glucopyranosyl-N-acetylgalactosamine
the only acid stable in Lancefield group Antigen
S.agalactiae (B)
C carbohydrate (polysaccharide) in the cell wall
Lancefield Classification
Group A
S.pyogenes
Group B
S.agalactiae
Group C
S.dysagalactiae
Group D
S.bovis group
Group A, C, F, G, N
Anginosus
Mutans
Mitis
Salivarius
streptococcus that does not have antigen
S.pneumoniae
S.pneumoniae is also part of ____
viridans group
8 virulence factor of GAS
- M protein
- Protein F & Lipoteichoic Acid
- Hyaluronic Acid Capsule
4.Streptolysin O and S - Deoxyribonuclease
- Streptokinase
7.Hyaluronidase - Streptococcal Pyrogenic Exotoxins
M protein is encoded by the genes
emm
resist phagocytosis & adherence to mucosal cells
M protein
adherence to epithelial cells
Protein F and Lipoteichoic Acid
Meaning of Protein F
Fibronectin binding protein
impede phagocytosis
most noticeable in very young cultures
Hyaluronic ACid Capsule
SLO anaerobic or aerobic?
anaerobic
SLS anaerobic or aerobic
aerobic
O hemolysin: _
oxygen labile
S hemolyis: _
oxygen stable
cells lysed: leukocytes, platelets, and other cells as well as RBcs
SLO
cells lysed: leukocyetes
SLS
highly immunogenic
SLO
non-immunogenic
SLS
Ab detected by:
Anti-streptolysisn O (ASO) test
potent protease
Deoxyribonuclease
most common DNase
B
DNase immunogenic?
yuh
Fibrinolysin
Streptokinase
lysis of fibrin clots through the action on plasminogen-plasmin-lyses clot
streptokinase
allows bacteria to escape from blood clots
streptokinase
immunogenic but not specific to GAS (can be found in Group C & Group G
Streptokinase
spreading factor
Hyaluronidase
enzyme that solubilize the ground substance of mammalian connective tissues
Hyaluronidase
cause a red spreading rash
Streptococcal Pyrogenic Infections
red spreading rash referred to as ___
erythrogenic toxin (scarlet fever)
-flat
-deep
-indistinct tissue
cellulites
-raised
-superficial
-clear, well defined borders
Erysipelas
most common GAS infection
Bacterial pharyngitis
impetigo,cellulites, erysipelas, wound infection, arthritis, scarlet fever
pyodermal infection
Type 2 “flesh eating bacteria”
Necrotizing Fascitis
-SpeA
-M1 and M3
Streptococcal Toxic Syndrome
rheumatic fever n acute glomerulonephritis
poststreptococcal sequelae
Treatment of choice:
penicillin