Streptococci Flashcards

1
Q

3 streps in this lecture?

A

pyogenes, agalactiae, pneumoniae

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2
Q

Is strep an aerobe, anaerobe, or facultative anerobe?

A

Facultative anerobe

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3
Q

How does alpha hemolysis look on blood agar plate?

A

Green

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4
Q

How does beta hemolysis look on blood agar plate?

A

clear

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5
Q

How does gamma hemolysis look on blood agar plate?

A

Almost like there’s no hemolysis

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6
Q

Strep pyogenes is in what Lancefield group?

A

Group A strep (GAS) and beta hemolytic

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7
Q

Strep agalactiae is in what group?

A

Group B strep (GBS) and also beta hemolytic

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8
Q

Strep pneumoniae and strep viridans are in what group?

A

Untypable using this system, alpha hemolytic

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9
Q

Catalase/coagulase tests for strep are?

A

Negative/negative

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10
Q

What are Lancefield antigens?

A

Characterize Strep on the basis of reaction of antibodies to species specific antigens (serology)

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11
Q

Group A strep has what kind of capsule?

A

Hyaluronic acid capsule

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12
Q

What protien is a group A strep virulence factor and can lead to rheumatic heart disease from molecular mimicry?

A

M protein

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13
Q

This Group A strep virulence factor is an adhesin and also a PAMP

A

Lipotechoic acid (LTA)

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14
Q

What virulence factor is strep’s superantigen?

A

Streptococcal pyrogenic exotoxin A (SpeA)

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15
Q

Very common strep infection that occurs in the throats of children

A

Pharyngitis (strep throat)

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16
Q

How do you treat pharyngitis?

A

Give penicillin to prevent development of ARF

17
Q

What can follow a pharyngeal infection with group A beta hemolytic strep?

A

Acute rheumatic fever

18
Q

This disease became almost obliterated when docs started washing their hands inbetween delivering babies

A

Endometritis

19
Q

This strep infection is a pyoderma (purulent skin infection) that is common in children

A

GAS impetigo

20
Q

Deeper impetigo with ulceration is known as

A

Ecthyma

21
Q

This streptococcal cellulitis is characterized by erythema and edema with rapidly advancing, well demarcated edges

A

Erysipelas

22
Q

This strep infection is an acute inflammatory condition of the skin that is deeper than impetigo or erysipelas.

A

Cellulitis

23
Q

Signs of cellulitis?

A

Localized pain, erythema, swelling, and heat

24
Q

This streptococcal induced infection is rapidly spreading and very fatal. It is characterized by EXTREME PAIN OUT OF PROPORTION TO THE APPEARANCE OF THE LESION

A

Necrotizing fasciitis

25
Q

How fast can necrosis spread with necrotizing fasciitis?

A

1 inch per hour

26
Q

ARF usually develops after

A

Pharyngitis

27
Q

Guidelines for diagnosis of ARF (acute rheumatic fever) are?

A

Jones criteria

28
Q

Treatment of strep pyrogenes?

A

Penicillin

29
Q

Invasive infections by strep pyogenes require what 4 things?

A
  1. you must monitor CO and BP
  2. IV infusion for hypotension
  3. Renal failure may call for dialysis
  4. IV Ig
30
Q

Test for Strep agalactiae (GBS)?

A

CAMP test

31
Q

Bigtime GBS virulence factor?

A

Capsule, capsule, capsule

32
Q

Viridans strep is alpha or beta hemolytic?

A

alpha

33
Q

Where on your body is viridans strep?

A

oral cavity

34
Q

How do you distinguish strep viridans from pneumococci?

A

Viridans is resistant to optochin

35
Q

Endocarditis of damaged heart valves usually occurs from?

A

viridans strep.. after a dental procedure, you get bacteremia

36
Q

These organisms are commensals of the GI tract

A

Enterococcus

37
Q

Leading cause of nosocomial infection

A

Enterococcus

38
Q

Why are enterococci a big problem?

A

They are very proficient at taking up DNA and passing it to other species. Enterococci is probably the reason that S. aureus can be vancomycin resistant