Strep Flashcards
What are the viridans?
Normal flora of oral cavity
What are the distinguishing feature of the S.pyogens?
B hemolytic, bacitracian s, PYR (+).
Pathogenesis of S.pyogens?
Hyalurinic acid - not immuno
M protein - antiphagocytosis
Streptolysin O - immuno
Streptolysin S - not immuno.
Spreading factors of S.pyogens?
Streptokinase - breaks down fibrin clot.
Streptococcal DNase - liquifies pus and extension in skin and soft tissue.
Hyaluronidase - hydrolyze ground substanse of connective tissue.
Exotoxin (A-C) phage code, fever and rash of scarlet fever.
Suppurative diseases of S.pyogens?
Pharingitis تضخم بالغدد اللمفاوية
Scarlet fever- sandpaper rash, circumoral pallor, strawbary tongue
Pyoderma, impetigo (honey)
Cellulitis, necrotizing fascitis, puerperal fever, lymphangitis, erysiplas.
Nonsuppurative diseases of S.pyogens?
Rheumatic fever- chorea later, type 2 hypersensitivity, 2 weak after pharingitis.
Glomerulonephritis- smoky urine, type 3 hypersensitivity.
Diagnosis og S.pyogens?
ELISA test, antibody to streptolysin O (RF), Anti-DNAse B and antihyaluronidase (for acute GN).
What are the Distinguishing Features of S.agalacteae?
B hemo, bacitracian R, hydrolyze hippurate, CAMP(+).
Resrvoir of S.agalacteae?
Vagina, GI tract
Pathogenesis of S.agalacteae?
Capsule, B hemo, CAMP
Diseases of S.agalacteaea?
Meningitis, septicemia, pneumonia.
What are the distinguishing feature of Streptococcus pneumoniae?
- a hemolytic
- Optochin sensitive
- Lancet-shaped diplococci
- Lysed by bile (bile soluble)
Reservoir of S.pneumonia?
Upper respiratory tract.
What are the pathogenesis of S.pneumonia?
- Polysaccharide capsule is the major virulence factor
- IgA protease
- Teichoic acid
- Pneumolysin O
Diseases of S.pneumonia?
Meningitis, otitis media, pneumonia (bloody sputum), sinusitis.
Diagnosis of S.pneumonia?
Gram stain, culture of CSF or sputum, quellung reaction, latex particle aggulutnation, urinary antigen test.
What are the distinguishing feature of Viridans Streptococci?
- a hemolytic
- Optochin resistant
- PYR-negative
- Bile insoluble
What are the resorvoir of Viridans Streptococci?
Human nasopharynx and colon
Diseases of Viridans Streptococci?
Dental caries, infective endocarditis(subacute).
