Storage and Replication of Genetic Information Flashcards
Structure of DNA and RNA The organisation of the genome DNA replication
Compare the structures of DNA and RNA (4Points)
- Double stranded vs Single stranded
- High molecular weight vs Heterogeneous in size
- Deoxyribose vs Ribose
- ATCG VS AUCG
Compare the sugars uses in DNA and RNA
RNA has a OH group on C2 whereas DNA has a H group - it lacks a O (deoxidised)
What joins nucleotides together
Phosphodiester Linkages between 3’ and 5’ carbons.
Why is RNA unstable
It has OH on ribose C2 which is attacked by water causing a break in the sugar-phosphate backbone.
What does the OH group on the C2 of RNA act as
A Lewis base or electron base donor
Why is DNA a Longterm store of genetic information
It is very stable. E.G frozen mammoth DNA can be obtained
What Bases are pyrimidines, and which are purines
C and T are pyrimidines
A and G are purines
Why is it important that a purine and pyrimidine nucleotide are based together
There is only space for one double ring base (purine) and one single ring base (pyrimidine)
What hold the 2 helices (strands) of DNA together
Hydrogen bonding between complimentary base pairs
