Storage and distribution Flashcards
What is Good Distribution Practice?
That part of quality assurance which ensures that products are consistently stored, transported and handled under suitable conditions
Inadequately controlled environments can lead to what?
ineffective medicines
spoiled produce
damaged materials
critical equipment failures
Aspirin breaks down into what?
salicylic acid and vinegar
Why are bathroom cabinets an ineffective way of storing medicines?
Too much heat and humidity
Considerable temperature cycling
Why are cotton ball plugs an ineffective way of storing medicines?
Pull moisture into the bottle
Harbour microorganisms
What are the 6 threats to quality?
Manufacture Microbiological Biological Chemical Temperature Sinister-malicious intent
What 2 organisms caused 3 babies to die in a german hospital after infecting a drip?
Enterobacter cloacae
Escherichia hermanii
What things can cause biological issues?
Insects and rodents
What can be controlled to prevent biological issues?
Humidity
Food sources
Clean and tidy
Pest control measures-traps
What are cold chain products?
Medicinal products that need to be stored and shipped at lower than ambient temperatures to assure their quality and efficacy
What drugs are high risk of damage from freezing or elevated temperatures?
Vaccines Insulin PN Biotech medicines Blood products
What is the temp range for a pharmaceutical refrigerator?
2 to 8 oC
What is the temp range for a blood bank refrigerator?
2 to 6oC
What is the temp range for a domestic fridge?
0-10oC
How big should the gap at the bottom of a refrigerator be?
3 inches
