STIs (Exam #3) Flashcards
What organism involves fibronectin coat?
Treponema pallidum = Syphilis
- STI
What are three characteristics of a Chancre, and what organism is it associated with?
Treponema pallidum = Syphilis (STI)
- Firm
- Raised edges
- Indurated
What signs/sxs are seen with Primary Syphilis?
Chancre
What signs/sxs are seen with Secondary Syphilis (2)?
- Maculopapular rash
- Condyloma lata
What signs/sxs are seen with Tertiary Syphilis (3)?
- Neurosyphilis
- Cardiovascular syphilis
- Granulomata (gummas)
What stage of latency in Syphilis is more associated with relapse/progression to Tertiary Syphilis?
EARLY latency (within 1 year of infection)
What are the three primary diagnostic tools used for Syphilis?
- CLINICAL = chancre
- Nontreponemal tests = VDRL, RPR
- Treponemal tests (specific) = FTA-ABS
What three symptoms are associated with Congenital Syphilis?
- Maculopapular rash
- Infectious nasal discharge
- Nasal bone osteitis
What are the three components of Hutchinson’s triad, and what organism is it associated with?
Treponema pallidum = Syphilis (STI)
- Notched incisors
- Interstitial keratitis
- Deafness (8th nerve)
What organisms involves the triad of notched incisors, interstitial keratitis, deafness (8th nerve), and what is this triad called?
Hutchinson’s triad
- Treponema pallidum = Syphilis (STI)
Is Treponema pallidum = Syphilis G- or G+?
G-
Is Neisseria gonorrheae = Gonorrhea G- or G+?
G-
Which STI organism needs lysed RBCs to grow?
Neisseria gonorrheae = Gonorrhea
What organism involves antigenic variation of pili, LOS and peptidoglycan?
Neisseria gonorrheae = Gonorrhea
- STI
What STI organism involves micro purulent discharge?
Neisseria gonorrheae = Gonorrhea
What STI organism involves complications of acute salpingitis/PID and DGI (fever, rash, purulent arthritis)?
Neisseria gonorrheae = Gonorrhea
Which STI organism needs host ATP to grow?
Chlamydia trachomatis = Chlamydia
What organism involves complication of lymphogranuloma venereum?
Chlamydia trachomatis = Chlamydia
- STI
What is the gold standard diagnostic test for Neisseria gonorrheae = Gonorrhea?
NAAT
What is the gold standard diagnostic test for Chlamydia trachomatis = Chlamydia? What is an alternative tool?
Cell culture isolation
- Can also use NAAT
What organism involves inclusion conjunctivitis in newborns?
Chlamydia trachomatis = Chlamydia
- STI
Which three STIs are ulcerative?
- Syphilis
- Chancroid
- Genital Herpes
Which three STIs are non-ulcerative?
- Gonorrhea
- Trichomoniasis
- Chlamydia
Is Chlamydia trachomatis = Chlamydia G- or G+?
G-
What STI organism is an anaerobe that presents with yellow-grey discharge?
Trichomonas vaginalis = Vaginitis
What organism involves clear discharge in males; frothy, malodorous discharge in females?
Trichomonas vaginalis = Vaginitis
- STI
What condition presents with pH change and is NOT an STI?
Bacterial Vaginosis
How can you differentiate Trichomonas vaginalis = Vaginitis from Bacterial Vaginosis (2)?
- pH 4.5+
- Presence of clue cells
What condition presents with clue cells?
Bacterial Vaginosis
What organism involves thick, white, frothy discharge with NO odor?
Candida albicans = Vulvovaginal Candidiasis
What organism presents similarly to Syphilis, but involves a Chancroid?
Haemophilus ducreyi = Chancroid
What organism involves a soft chancre (Chancroid)?
Haemophilus ducreyi = Chancroid
What are three characteristics of a Chancroid, and what organism is it associated with?
- Soft (NOT raised)
- Ragged edges
- Sharp margins
What is the diagnosis for Haemophilus ducreyi = Chancroid?
PCR
How can you differentiate a Chancre (Treponema pallidum = Syphilis) from Chancroid (Haemophilus ducreyi) (4)?
- Chancre = Syphilis: HARD, RAISED edges; LOCAL and DEEPER
- Chancroid = H. ducreyi: SOFT, RAGGED edges; SPREADS easily and EXPANDS
What are the two possible organisms that use Pelvic Inflammatory Disease (PID)?
- N. gonorrheae
- C. trachomatis
What is the primary symptom associated with Pelvic Inflammatory Disease (PID)?
Lower abdominal pain
