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MICRO > STIs (Exam #3) > Flashcards

STIs (Exam #3) Flashcards

1
Q

What organism involves fibronectin coat?

A

Treponema pallidum = Syphilis

- STI

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2
Q

What are three characteristics of a Chancre, and what organism is it associated with?

A

Treponema pallidum = Syphilis (STI)

  • Firm
  • Raised edges
  • Indurated
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3
Q

What signs/sxs are seen with Primary Syphilis?

A

Chancre

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4
Q

What signs/sxs are seen with Secondary Syphilis (2)?

A
  • Maculopapular rash

- Condyloma lata

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5
Q

What signs/sxs are seen with Tertiary Syphilis (3)?

A
  • Neurosyphilis
  • Cardiovascular syphilis
  • Granulomata (gummas)
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6
Q

What stage of latency in Syphilis is more associated with relapse/progression to Tertiary Syphilis?

A

EARLY latency (within 1 year of infection)

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7
Q

What are the three primary diagnostic tools used for Syphilis?

A
  • CLINICAL = chancre
  • Nontreponemal tests = VDRL, RPR
  • Treponemal tests (specific) = FTA-ABS
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8
Q

What three symptoms are associated with Congenital Syphilis?

A
  • Maculopapular rash
  • Infectious nasal discharge
  • Nasal bone osteitis
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9
Q

What are the three components of Hutchinson’s triad, and what organism is it associated with?

A

Treponema pallidum = Syphilis (STI)

  • Notched incisors
  • Interstitial keratitis
  • Deafness (8th nerve)
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10
Q

What organisms involves the triad of notched incisors, interstitial keratitis, deafness (8th nerve), and what is this triad called?

A

Hutchinson’s triad

- Treponema pallidum = Syphilis (STI)

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11
Q

Is Treponema pallidum = Syphilis G- or G+?

A

G-

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12
Q

Is Neisseria gonorrheae = Gonorrhea G- or G+?

A

G-

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13
Q

Which STI organism needs lysed RBCs to grow?

A

Neisseria gonorrheae = Gonorrhea

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14
Q

What organism involves antigenic variation of pili, LOS and peptidoglycan?

A

Neisseria gonorrheae = Gonorrhea

- STI

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15
Q

What STI organism involves micro purulent discharge?

A

Neisseria gonorrheae = Gonorrhea

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16
Q

What STI organism involves complications of acute salpingitis/PID and DGI (fever, rash, purulent arthritis)?

A

Neisseria gonorrheae = Gonorrhea

17
Q

Which STI organism needs host ATP to grow?

A

Chlamydia trachomatis = Chlamydia

18
Q

What organism involves complication of lymphogranuloma venereum?

A

Chlamydia trachomatis = Chlamydia

- STI

19
Q

What is the gold standard diagnostic test for Neisseria gonorrheae = Gonorrhea?

A

NAAT

20
Q

What is the gold standard diagnostic test for Chlamydia trachomatis = Chlamydia? What is an alternative tool?

A

Cell culture isolation

- Can also use NAAT

21
Q

What organism involves inclusion conjunctivitis in newborns?

A

Chlamydia trachomatis = Chlamydia

- STI

22
Q

Which three STIs are ulcerative?

A
  • Syphilis
  • Chancroid
  • Genital Herpes
23
Q

Which three STIs are non-ulcerative?

A
  • Gonorrhea
  • Trichomoniasis
  • Chlamydia
24
Q

Is Chlamydia trachomatis = Chlamydia G- or G+?

A

G-

25
Q

What STI organism is an anaerobe that presents with yellow-grey discharge?

A

Trichomonas vaginalis = Vaginitis

26
Q

What organism involves clear discharge in males; frothy, malodorous discharge in females?

A

Trichomonas vaginalis = Vaginitis

- STI

27
Q

What condition presents with pH change and is NOT an STI?

A

Bacterial Vaginosis

28
Q

How can you differentiate Trichomonas vaginalis = Vaginitis from Bacterial Vaginosis (2)?

A
  • pH 4.5+

- Presence of clue cells

29
Q

What condition presents with clue cells?

A

Bacterial Vaginosis

30
Q

What organism involves thick, white, frothy discharge with NO odor?

A

Candida albicans = Vulvovaginal Candidiasis

31
Q

What organism presents similarly to Syphilis, but involves a Chancroid?

A

Haemophilus ducreyi = Chancroid

32
Q

What organism involves a soft chancre (Chancroid)?

A

Haemophilus ducreyi = Chancroid

33
Q

What are three characteristics of a Chancroid, and what organism is it associated with?

A
  • Soft (NOT raised)
  • Ragged edges
  • Sharp margins
34
Q

What is the diagnosis for Haemophilus ducreyi = Chancroid?

A

PCR

35
Q

How can you differentiate a Chancre (Treponema pallidum = Syphilis) from Chancroid (Haemophilus ducreyi) (4)?

A
  • Chancre = Syphilis: HARD, RAISED edges; LOCAL and DEEPER

- Chancroid = H. ducreyi: SOFT, RAGGED edges; SPREADS easily and EXPANDS

36
Q

What are the two possible organisms that use Pelvic Inflammatory Disease (PID)?

A
  • N. gonorrheae

- C. trachomatis

37
Q

What is the primary symptom associated with Pelvic Inflammatory Disease (PID)?

A

Lower abdominal pain

MICRO (11 decks)

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