STIs Flashcards

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1
Q

How are infections transmitted during sex?

A
  • sexual/genital secretions
  • direct innoculation e.g. HSV
  • trauma e.g. Hep C
  • ingestion
  • fomites e.g. sex toys
  • injection drug use
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2
Q

List some risk factors for STIs:

A
  • <25 years old
  • change sexual partner
  • non-condom use
  • men who have sex with men
  • past history of STI
  • large urban areas
  • social deprivation
  • black ethnicity
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3
Q

Which STIs affect the mouth

A
  • chlamydia
  • gonorrhoea
  • syphilis
  • herpes simplex virus
  • human papillomavirus
  • human immunodeficiency virus
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4
Q

What is the classical sign of primary syphilis?

How does secondary syphilis present in the mouth?

Diagnosis?

Treatment?

A

Chancre - seen at site of infection, 70% painless, can be seen in the mouth

  • cant fold in half, undulated, button like

Secondary syphilis:

  • white glistening patches, greyish membrane, hyperaemic halo, snail track ulcers
  • present on soft/hard palate, buccal mucosa, tongue

Diagnosis:

  • lesion - swab for treponema pallidum by PCR
  • venous blood - antibody and confirmatory tests

Treatment:

  • antibiotic - benzathene penicillin or doxycycline

WEAR GLOVES WHEN TREATING PTS WITH SYPHILIS

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5
Q

How can HIV be transmitted?

Who are the high risk groups?

A
  • mostly sexual transmission
  • injection use

Everyone is at risk:

  • men sex with men
  • high prevalence countries
  • injecting drugs
  • sexual contact of above
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6
Q

How may primary HIV present?

A
  • upto 80% present with symptoms
  • onset average 2-4 weeks after infection
  • combination of fever, rash, myalgia, pharyngitis, headache
  • very high risk of onward transmission

Oral lesions:

  • aphthous ulcers
  • candidiasis
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7
Q

How may mucosal candidiasis present in HIV?

A

Mucosal candidiasis:

  • pseudomembranous
  • erythematous
  • angular cheilitis
  • oesophageal extension
  • predictive of progression to AIDS
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8
Q

How may gingivitis present in symptomatic HIV?

A

Gingiviitis:

  • linear gingival erythema
  • necrotising ulcerative periodontitis
  • often sudden onset
  • absence of plaque/calculus
  • relating to other lifestyle issues including IV drug use
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9
Q

How may kaposi’s sarcoma present as symptomatic HIV?

Oral Leukoplakia?

Anything else?

A

Kaposi’s sarcoma

  • vascular tumour
  • caused by human herpes virus 8

Oral hairy leukoplakia - associated with EBV

  • predictor of progression to AIDS
  • may have candida co-infection

Seborrhoeic dermatitis

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10
Q

How do you test for HIV?

How to care for people with HIV?

A

HIV testing:

  • blood test - possible false negative in first 6 weeks
  • specific verbal consent to test for HIV

Caring for people with HIV:

  • ask patients if they are on treatment
  • beware of drug-drug interactions
  • do not be scared of patients with HIV
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11
Q

Which HPV strains increase the risk of oropharyngeal/cervical cancers?

A
  • HPV16 and HPV18 strains are oncogenic
  • alcohol and smoking add to risk
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