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Pharm Y2S1 > STIs > Flashcards

STIs Flashcards

1
Q

What is the most common STI in the UK?

A

Chlamydia

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2
Q

What is the full name of the bacteria responsible for causing chlamydia?

A

Chlamydia trachomatis

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3
Q

What percentage of chlamydia sufferers are thought to be asymptomatic?

A

50% of men

70% of women

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4
Q

What are the symptoms of chlamydia?

A 
Pain passing urine
White, cloudy discharge
Testicle pain
Itchy vulva
Irregular bleeding
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5
Q

What are the complications of chlamydia if untreated?

A

Pelvic inflammatory disease
Tubal factor infertility
Ectopic pregnancy
Chronic pelvic pain

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6
Q

What is the treatment for chlamydia?

A 
Single dose 1g azithromycin
OR
100mg doxycycline bd for 7 days
OR
500mg erythromycin bd for 14 days
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7
Q

What is urethritis?

A

Inflammation of the urethra more commonly in men

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8
Q

What are the potential causative organisms of urethritis?

A

Neisseria gonorrhoea
Chlamydia trachomatis
Ureaplasma urealyticum
Mycoplasma genitalum

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9
Q

What are the symptoms of urethritis?

A 
Dysuria
Inflamed foreskin
White/yellow discharge
Testicle swelling
Abdominal pain
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10
Q

What is the exceptional symptom for non-gonococcal urethritis?

A

Penile tip irritation

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11
Q

What is the treatment for gonococcal urethritis?

A

Ceftriaxone 500mg IM OR cefixime 400mg PO

AND azithromycin 1g PO

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12
Q

What is the standard treatment for non-gonococcal urethritis?

A

Treat as for chlamydia as it is usually the cause with 1g of azithromycin.

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13
Q

What are the risk factors for bacterial vaginosis?

A

Sexual activity
Smoker
Black
IUD

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14
Q

What is the cause of bacterial vaginosis?

A

Anaerobic organisms proliferating due to washing away of normal flora, increasing pH.

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15
Q

What is the characteristic symptom of bacterial vaginosis?

A

White ‘fishy’ discharge.

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16
Q

What is the treatment for bacterial vaginosis?

A

Metronidazole 400mg bd for 7 days
OR
Clindamycin 300mg bd for 7 days
Available for oral use or as intravaginal gels

17
Q

What are the methods of transmission of trichomoniasis?

A

Transmitted via sex and sharing towels, more common in women.

18
Q

What is the causative organism of trichomoniasis?

A

Protazoa trichomoniasis vaginalis

19
Q

What proportion of sufferers of trichomoniasis are asymptomatic?

A

10-50%

20
Q

What are the symptoms of trichomoniasis?

A

Yellow, frothy discharge
Unpleasant smell
Itchy/sore vuvla
Dysuria

21
Q

What is the treatment for trichomoniasis?

A

Metronidazole 2g as a single dose OR 400mg bd for 7 days

22
Q

What are herpetic lesions on the hands?

A

Whitlows

23
Q

What are the symptoms of herpes?

A

Blisters

Flu like symptoms

24
Q

What is the treatment for genital herpes?

A

Doesn’t cure it but can improve symptoms
Aciclovir 500mg 5 times a day for 5 days
Topical 5% cream available

25
Q

What is stage 1 of the syphilis infection?

A

0-90 days- painless but highly infective ulcer. Lymphadenopathy heals without treatment in 2-6 weeks.

26
Q

What is stage 2 of the syphilis infection?

A

4-10 weeks- non irritating rash on chest, back and palms. Lymph node enlargement and wart like genital growths.

27
Q

What is stage 3 of the syphilis infection?

A

3-15 years- neurological disease, soft tumour like growths (gumma), chancre development at site of infection

28
Q

How is early syphilis treated?

A

IM benzathine penicillin G 2.4MU

IM procaine penicillin G 600000UI for 10 days

29
Q

How is syphilis treated in penicillin allergic patients?

A

100mg doxycycline bd for 7/14 days

30
Q

How is latent syphilis treated?

A

Prevention of neurological involvement
IM benzathine penicillin G 2.4MU for 14 days
IM procaine penicillin G 600000UI for 17 days

31
Q

What is the cause of anogenital warts?

A

HPV

32
Q

What are the symptoms of anogenital warts?

A

Smooth, flat bumps
Large cauliflower like lumps
Painless but itchy

33
Q

How are soft non keratinised anogenital warts treated?

A

Podophyllotoxin and trichloroacetic acid 0.5% cream
bd for 3 days, weekly for 5 weeks
OR
3 times weekly at night for up to 16 weeks

34
Q

How are keratinised anogenital warts treated?

A

Respond to ablative therapy

Pharm Y2S1 (8 decks)

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